Apocrine gland adenoma and adenocarcinoma of the axilla.
Apocrine gland adenoma and adenocarcinoma of the axilla.
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顶浆腺腺瘤和腋窝腺癌。
DOI：
10.1097/00006534-197812000-00098
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发表时间：
1978
影响因子：
--
通讯作者：
E. B. Helwig
中科院分区：
文献类型：
--
作者：
E. Courtiss;R. L. Warkel;E. B. Helwig
本文报告12例腋窝顶泌腺肿瘤的临床和病理资料。根据组织学特征，两个肿瘤被归类为腺瘤和腺癌。所有的肿瘤的特点是腺排列的大细胞丰富的嗜酸性细胞质和证据的断头分泌。肿瘤细胞胞浆内含有PAS阳性、抗胰蛋白酶的颗粒。胞浆内铁颗粒在10个肿瘤中的3个中是可证实的。对所有12例患者进行了随访。两名大汗腺腺瘤患者均健在。两名腺癌患者在诊断后不久死于不相关的原因。在其余8例腺癌患者中，3例死于疾病，1例患有骨转移。肿瘤分化与预后之间似乎存在相关性。
Apocrine tumors from the axilla of 12 patients were studied clinically and pathologically. Based on histologic features, two tumors were classified as adenomas and ten as adenocarcinomas. All of the neoplasms were characterized by a glandular arrangement of large cells with abundant eosinophillic cytoplasm and evidence of decapitation secretion. The cytoplasm of the tumor cells contained PAS-positive, diastase-resistant granules. Intracytoplasmic particles of iron were demonstrable in three of ten tumors. Follow-up was available for all 12 patients. The two patients with apocrine adenoma are alive and well. Two patients with adenocarcinoma died of unrelated causes shortly after diagnosis. Of the remaining eight patients with adenocarcinoma, three have died of disease, and one is living with skeletal metastasis. A correlation appears to exist between tumor differentiation and prognosis.