Universal cervical length screening and treatment with vaginal progesterone to prevent preterm birth: a decision and economic analysis.
Universal cervical length screening and treatment with vaginal progesterone to prevent preterm birth: a decision and economic analysis.
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DOI:
10.1016/j.ajog.2009.12.005
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发表时间:
2010-06
影响因子:
9.8
通讯作者:
Romero R
中科院分区:
文献类型:
--
作者:
Cahill AG;Odibo AO;Caughey AB;Stamilio DM;Hassan SS;Macones GA;Romero R
To estimate which strategy is the most cost-effective for prevention of preterm birth and associated morbidity. We used decision-analytic and cost-effectiveness analyses to estimate which of 4 strategies was superior based on quality-adjusted life-years (QALYs), cost in US dollars ($), and number of preterm births prevented. Universal sonographic screening for cervical length and treatment with vaginal progesterone was the most cost-effective strategy and dominant over 3 alternatives: cervical length screening for women at increased risk for preterm birth and treatment with vaginal progesterone; risk-based treatment with 17 α-hydroxyprogesterone Caproate (17-OHP-C) without screening; no screening or treatment. Universal screening represented savings of $1,339 ($8,325 vs. $9,664) when compared to treatment with 17-OHP-C, and led to a reduction of 95,920 preterm births annually in the US. Universal sonographic screening for short cervical length and treatment with vaginal progesterone appears cost-effective and yields the greatest reduction in preterm birth prior to 34 weeks.
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DOI:
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发表时间:
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影响因子:
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