Effects of leisure activities and psychosocial support on medication adherence and clinic attendance among children on antiretroviral therapy
Effects of leisure activities and psychosocial support on medication adherence and clinic attendance among children on antiretroviral therapy
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DOI：
10.2147/hiv.s64964
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发表时间：
2014-01-01
影响因子：
1.5
通讯作者：
Anigilaje, Omolara Olufunmilayo
中科院分区：
文献类型：
--
作者：
Anigilaje, Emmanuel Ademola;Dabit, Othniel Joseph;Anigilaje, Omolara Olufunmilayo
背景：最佳地坚持抗逆转录病毒治疗（ART）和保留护理对于艾滋病毒管理至关重要。通过一个孩子的俱乐部（KC），该研究旨在评估社会休闲和社会心理支持对ART的依从性和诊所出勤率在儿科ART program.Methods的影响：这是一个描述性的纵向研究，在联邦医疗中心，马库尔迪，尼日利亚，从2011年6月至2012年6月进行。它包括33名有抗逆转录病毒治疗经验的儿童及其照顾者。除了研究报告之外，还进行了一次有12名讨论者参加的定性重点小组讨论。ART坚持，诊所出席，和临床和免疫病毒学反应的儿童ART注意到在6个月和12个月的follow-up.Results：儿童包括17名男性和16名女性，中位年龄为5岁。在定量（32/33，96.9%）和定性（12/12，100.0%）评估中，财务限制是失访的最常见原因。但是，如定性研究报告所述，交通工具的缺乏仍然可能压倒财政援助所能提供的好处。基线平均血红蛋白水平（8.50 g/dL），中位CD 4计数187.00个/mm（3）;身高中位体重z评分（-0.395），以及体重指数中位数（15.40）显著增加，6个月时分别为10.03 g/dL、1，030.00个细胞/mm（3）、-0.090和18.50（P值：0.000）和10.47 g/dL、1，203.00个细胞/mm 3、0.420和19.20（P值：0.000）。基线中位病毒载量（45，678.00拷贝/mL）也显著降低，6个月和12个月时降至200.00拷贝/mL（P值：0.000）。有没有磨损死亡或损失的后续行动，坚持艺术是100%，在6个月和12个月的following.Conclusion：通过KC，儿童保留在护理，具有良好的坚持艺术，良好的临床和免疫病毒学反应艺术，即使在以前失去了后续行动。
Background: Optimal adherence to antiretroviral therapy (ART) and retention-in-care are essential in HIV management. Through a Kiddies' Club (KC), the study aimed at assessing the impact of social leisures and psychosocial support on ART adherence and clinic attendance in a pediatric ART program.Methods: This was a descriptive, longitudinal study, conducted at the Federal Medical Centre, Makurdi, Nigeria, from June 2011 to June 2012. It included 33 ART-experienced children and their caregivers. The study was supplemented with a qualitative focused group discussion, involving 12 discussants. ART adherence, clinic attendance, and clinical and immunoviralogical responses of the children to ART were noted at 6 months and at 12 months of follow-up.Results: The children comprised 17 males and 16 females, with a median age of 5 years. Financial constraint was the most common reason given for losses to follow-up in quantitative (32/33, 96.9%) and qualitative (12/12, 100.0%) assessments. But, unavailability of means of transportation may still override the benefit that financial assistance can provide, as reported in the qualitative study. The baseline mean hemoglobin level (8.50 g/dL), median CD4 count (187.00 cells/mm(3)); median weight for height z-score (-0.395), and the median body mass index (15.40) increased significantly to respective values of 10.03 g/dL, 1,030.00 cells/mm(3), -0.090, and 18.50, at 6 months (P-values: 0.000), and 10.47 g/dL, 1,203.00 cells/mm3, 0.420, and 19.20, at 12 months (P-values: 0.000). The baseline median viral load (45,678.00 copies/mL) also decreased significantly, to 200.00 copies/mL at 6 months and at 12 months (P-values: 0.000). There was no attrition from death or loss to follow-up, and adherence to ART was 100%, at 6 months and at 12 months of follow-up.Conclusion: Through the KC, children were retained in care, with excellent adherence to ART, and good clinical and immunoviralogical responses to ART, even after being previously lost to follow-up.