The polymorphic phase behavior of dielaidoylphosphatidylethanolamine. Effect of n-alkanols.
The polymorphic phase behavior of dielaidoylphosphatidylethanolamine. Effect of n-alkanols.
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二反油酰磷脂酰乙醇胺的多晶型相行为。
DOI：
10.1016/0005-2736(89)90441-0
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Rowe,ES
中科院分区：
文献类型：
--
作者：
Veiro,JA;Khalifah,RG;Rowe,ES
用分光光度法和31P核磁共振研究了二来酰磷脂酰乙醇胺(DEPE)的多晶型相行为。结果表明，用分光光度法可观察到双层结构向倒六方结构的相变。用分光光度法研究了甲醇、乙醇和丙醇对凝胶向液晶转变和双层膜向倒六方转变的影响。结果表明，这些醇类使凝胶向液晶相转变的温度降低，而双层膜向倒六方相转变的温度向高温方向移动。用31P-核磁共振研究了DEPE的双层相和反六方相之间的结构转变。
The polymorphic phase behavior of dielaidoylphosphatidylethanolamine (DEPE) has been investigated using spectrophotometry and31P nuclear magnetic resonance (NMR). It has been demonstrated that the bilayer to inverted hexagonal phase transition can be observed by spectrophotometry. The effects of the methanol, ethanol, and propanol on both the gel to liquid crystal transition and the bilayer to inverted hexagonal transition were investigated by spectrophotometry. It was shown that these alcohols shift the gel to liquid-crystalline phase transition to lower temperature, whereas the bilayer to inverted hexagonal phase transition is shifted to higher temperatures by these alcohols. The structural transition between the bilayer and inverted hexagonal phase of pure DEPE was also investigated by31P-NMR.