Aseptic loosening in cemented custom-made prosthetic replacements for bone tumours of the lower limb
Aseptic loosening in cemented custom-made prosthetic replacements for bone tumours of the lower limb
复制标题
下肢骨肿瘤骨水泥定制假肢的无菌松动
DOI：
10.1302/0301-620x.78b1.0780005
复制
发表时间：
1996-01-01
影响因子：
--
通讯作者：
Walker, PS
中科院分区：
文献类型：
--
作者：
Unwin, PS;Cannon, SR;Walker, PS
我们对1001个骨肿瘤术后定制假体进行了回顾性研究，其中股骨远端假体493个，股骨近端假体263个，胫骨近端假体245个。无菌性松动是植入物失败的主要模式，71名患者因骨水泥髓内干无菌性松动进行了翻修。在股骨远端置换的患者中，患者无菌性松动存活120个月的概率为93.8%，股骨远端假体为67.4%，胫骨近端植入物为58%。患者手术时的年龄和骨切除的百分比与无菌性松动的风险有关。接受股骨远端假体置换率高的年轻患者，在无菌松动的情况下存活的预后最差。胫骨近端置换组的截骨百分率有显著影响，但患者的年龄没有显著影响，年龄和截骨百分率都不是股骨近端置换术后的影响因素。
We have made a retrospective study of 1001 custom-made prostheses used as replacements after surgery for bone tumours, There were 493 distal femoral, 263 proximal femoral and 245 proximal tibial prostheses. Aseptic loosening was shown to be the principal mode of failure of the implants, and 71 patients had revision for aseptic loosening of a cemented intramedullary stem.The probability of a patient surviving aseptic loosening for 120 months was 93.8% for a proximal femoral replacement, 67.4% for a distal femoral prosthesis and 58% for a proximal tibial implant, In patients with distal femoral replacements the age of the patient at the time of operation and the percentage of bone resected were related to the risk of aseptic loosening. Young patients with distal femoral prostheses in whom a high percentage of the femur had been replaced had the poorest prognosis for survival without aseptic loosening. The percentage of bone removed had a significant effect in the proximal tibial replacement group, but the age of the patient did not, By contrast, neither the age nor the percentage of bone removed was a factor after proximal femoral replacement.The significance of these findings is discussed in relation to mechanical factors.