Construction of multiring frameworks by metal-free cascade reactions of stable isochromenylium tetrafluoroborate.
Construction of multiring frameworks by metal-free cascade reactions of stable isochromenylium tetrafluoroborate.
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DOI：
10.1021/jo902051g
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发表时间：
2009-10
期刊：
影响因子：
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通讯作者：
Zhi-Long Hu;Wenjian Qian;Shengke Wang;Shaozhong Wang;Z. Yao
中科院分区：
文献类型：
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作者：
Zhi-Long Hu;Wenjian Qian;Shengke Wang;Shaozhong Wang;Z. Yao
利用空气稳定的四氟硼酸异铬烯鎓与烯烃的级联反应，开发了构建多种多环骨架的有效方法。已经观察到将两当量的苯乙烯型烯烃连续加成到四氟硼酸异铬烯鎓(ICTB) 1 中，并提出并讨论了其机理。通过预先设计的杂原子或弗里德尔-克来福特供体对早期阳离子中间体的分子内捕获提供了两种不同类型的桥环系统。
Efficient methodologies for constructing several multiring frameworks have been developed utilizing the cascade reactions of air-stable isochromenylium tetrafluoroborates with olefins. Successive additions of two equivalents of styrene-type olefins to isochromenylium tetrafluoroborate (ICTB) 1 have been observed and their mechanisms were proposed and discussed. Intramolecular capture of the early stage cationic intermediates by predevised heteroatoms or Friedel-Crafts donors provided two different types of bridged-ring systems.