HUMAN PROSTATIC ACID-PHOSPHATASE - SELECTED PROPERTIES AND PRACTICAL APPLICATIONS
HUMAN PROSTATIC ACID-PHOSPHATASE - SELECTED PROPERTIES AND PRACTICAL APPLICATIONS
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DOI：
10.1016/0009-8981(94)90209-7
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发表时间：
1994-05-01
影响因子：
5
通讯作者：
KUCIEL, R
中科院分区：
文献类型：
--
作者：
OSTROWSKI, WS;KUCIEL, R
人前列腺酸性磷酸酶（EC 3.1.3.2）是一种非特异性磷酸单酯酶，在雄激素控制下合成并分泌到精浆中。该酶是分子量约为100 kDa的二聚体。编码这种蛋白质的基因位于3号染色体上。多年来，前列腺磷酸酶一直被用作前列腺癌诊断和治疗控制的标志物。然而，这种酶的生物学作用仍然未知，需要进一步探索。
Human prostatic acid phosphatase (EC 3.1.3.2) is a non-specific phosphomonoesterase, synthetized and secreted into seminal plasma under androgenic control. The enzyme is a dimer of molecular weight around 100 kDa. Gene coding this protein is localized on chromosome 3. Since many years prostatic phosphatase has been used as a marker for diagnosis and therapy control of cancer of the prostate gland. The biological role of this enzyme, however, remains unknown and needs further exploration.