Fluoride Retention in Proximal Plaque and Saliva Using Two NaF Dentifrices Containing 5,000 and 1,450 ppm F with and without Water Rinsing
Fluoride Retention in Proximal Plaque and Saliva Using Two NaF Dentifrices Containing 5,000 and 1,450 ppm F with and without Water Rinsing
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DOI：
10.1159/000201592
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发表时间：
2009-01-01
期刊：
影响因子：
4.2
通讯作者：
Birkhed, D.
中科院分区：
文献类型：
--
作者：
Nordstrom, A.;Birkhed, D.
共有26名健康志愿者参加了这项随机四腿交叉研究，旨在测量牙间菌斑和唾液中的氟化物（F）保留。使用两种NaF溶液（5，000和1，450 ppm F），有和没有刷牙后水冲洗。4种刷牙方法每天进行两次，持续2周。每种方法后，使用牙线从所有近端部位收集牙间菌斑。在牙菌斑采样后，立即要求受试者用相同的牙膏刷牙，并使用刷牙后的水冲洗程序。在刷牙前和刷牙后60分钟内，使用小纸尖从4个牙间部位收集近端唾液。本研究表明，5，000 ppm含氟牙膏刷牙后不用水冲洗导致牙菌斑和唾液中的氟浓度最高，1，450 ppm含氟牙膏用水冲洗最低。两种方法的唾液F浓度-时间曲线下面积相差4.2倍（p < 0.001）。每单位重量菌斑含氟量（n = 16）相差2.75倍（p < 0.05）。用5,000 ppm的氟刷牙后立即用水冲洗，可使唾液中的氟浓度降低2.4倍（p < 0.001）。5，000/冲洗和1，450/未冲洗之间唾液中F值的差异较小且不显著。使用含5，000 ppm F的牙膏而不使用刷牙后水冲洗，近端唾液和牙菌斑中F的增加可能具有临床意义。版权所有（C）2009 S. Karger AG，巴塞尔
A total of 26 healthy volunteers participated in this randomized 4-leg crossover study designed to measure fluoride (F) retention in interdental plaque and saliva. Two NaF dentifrices (5,000 and 1,450 ppm F) were used, with and without postbrushing water rinsing. The 4 tooth brushing methods were carried out twice a day during 2 weeks. Interdental plaque was collected from all proximal sites after each method, using dental floss. Immediately after the plaque sampling, the subjects were asked to brush their teeth with the same toothpaste and use the postbrushing water rinsing procedure as previously. Proximal saliva was collected from 4 interdental sites, using small paper points, before and up to 60 min after the brushing. The present study showed that the 5,000 ppm F toothpaste without postbrushing water rinsing resulted in the highest F concentration in both plaque and saliva and the 1,450 ppm F toothpaste with water rinsing in the lowest. The difference in the area under the curve of saliva F concentration versus time between the 2 methods was 4.2 times (p < 0.001). The corresponding difference in F concentration per unit weight of plaque (n = 16) was 2.75 times (p < 0.05). Water rinsing immediately after tooth brushing with 5,000 ppm reduced the F concentration in saliva by 2.4 times (p < 0.001). The difference in F values in saliva between 5,000/rinsing and 1,450/no rinsing was minor and not significant. The increase of F in both proximal saliva and plaque, using a dentifrice with 5,000 ppm F without postbrushing water rinsing, may be of clinical importance. Copyright (C) 2009 S. Karger AG, Basel