Uroporphyrin- and coproporphyrin I-accumulating mutant of Escherichia coli K12.
Uroporphyrin- and coproporphyrin I-accumulating mutant of Escherichia coli K12.
复制标题
大肠杆菌 K12 的尿卟啉和粪卟啉 I 累积突变体。
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
A. Sasarman
中科院分区：
文献类型：
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作者：
P. Chartrand;D. Tardif;A. Sasarman
通过新霉素筛选，从大肠埃希菌K12中分离出一种新的血液缺陷突变体。突变体缺乏尿卟啉原III辅合酶活性，这可以从尿卟啉I和同比例卟啉的积累中看出。p1介导的hemD基因定位表明，新基因位于大肠杆菌K12染色体图谱上ilv和cya之间的第83位。
A new type of haem-deficient mutant was isolated in Escherichia coli K12 by neomycin selection. The mutant was deficient in uroporphyrinogen III cosynthase activity as indicated by the accumulation of uroporphyrin I and coproporphyrin. The mapping of the corresponding hemD gene by P1-mediated transduction showed that the new gene was located between ilv and cya, at min 83 on the chromosomal map of Escherichia coli K12.