Protein translocation and thylakoid biogenesis in cyanobacteria
Protein translocation and thylakoid biogenesis in cyanobacteria
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DOI：
10.1016/j.bbabio.2015.08.010
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发表时间：
2016-03-01
影响因子：
4.3
通讯作者：
Robinson, Colin
中科院分区：
文献类型：
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作者：
Frain, Kelly M.;Gangl, Doris;Robinson, Colin
蓝细菌表现出一种复杂的膜分化形式，使它们与大多数细菌不同。许多过程发生在质膜，但光合作用的光捕获，电子传递和ATP合成发生在一个丰富的内部类囊体膜。这篇评论认为，这一系统的亚细胞区室化是如何维持的，以及蛋白质是如何针对不同的亚室，特别是质膜，周质，类囊体膜和类囊体腔。Sec-，达特-和信号识别颗粒-（SRP）依赖的蛋白质靶向途径的参与进行了讨论，连同可能参与的所谓的“自发”的插入膜蛋白的途径，以前的特征为叶绿体类囊体膜蛋白。蓝藻细胞生物学的一个有趣的方面是，大多数只包含一组编码Sec，达特和SRP组分的基因，但质膜和类囊体膜的蛋白质组是非常不同的。蛋白质分选机制的影响被认为是。本文是由Conrad Mullineaux教授编辑的题为细菌生物能量系统的组织和动力学的特刊的一部分。(C)2015 Elsevier B. V.版权所有。
Cyanobacteria exhibit a complex form of membrane differentiation that sets them apart from most bacteria. Many processes take place in the plasma membrane, but photosynthetic light capture, electron transport and ATP synthesis take place in an abundant internal thylakoid membrane. This review considers how this system of subcellular compartmentalisation is maintained, and how proteins are directed towards the various subcompartments specifically the plasma membrane, periplasm, thylakoid membrane and thylakoid lumen. The involvement of Sec-, Tat- and signal recognition particle-(SRP)-dependent protein targeting pathways is discussed, together with the possible involvement of a so-called 'spontaneous' pathway for the insertion of membrane proteins, previously characterised for chloroplast thylakoid membrane proteins. An intriguing aspect of cyanobacterial cell biology is that most contain only a single set of genes encoding Sec, Tat and SRP components, yet the proteomes of the plasma and thylakoid membranes are very different. The implications for protein sorting mechanisms are considered. This article is part of a Special Issue entitled Organization and dynamics of bioenergetic systems in bacteria, edited by Prof Conrad Mullineaux. (C) 2015 Elsevier B.V. All rights reserved.