Health-related quality of life predicts mortality in older but not younger patients following cardiac surgery
Health-related quality of life predicts mortality in older but not younger patients following cardiac surgery
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DOI：
10.1111/j.1076-7460.2005.04312.x
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发表时间：
2005-07-01
影响因子：
--
通讯作者：
Rumsfeld, JS
中科院分区：
文献类型：
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作者：
Ho, PM;Masoudi, FA;Rumsfeld, JS
研究人员评估了术前健康相关的生活质量，作为老年人心脏手术后 6 个月死亡率的预测因素。 （65 岁及以上）与年轻患者。采用按年龄组分层的多变量回归来比较来自 Short Form-36 健康状况调查的术前身体成分摘要和精神成分摘要分数与死亡率之间的关联。在老年患者的多变量分析中，较低的术前身体成分总结（比值比，1.54；95% 置信区间，1.19-2.00；p=0.01）和精神成分总结（比值比，1.26；95% 置信区间，1.06-1.49；p=0.03）评分与死亡率独立相关。相比之下，身体成分总结 (p=0.82) 和精神成分总结 (p=0.79) 评分均与年轻亚组的死亡率无关。这项研究表明，术前健康状况是老年患者心脏手术后死亡率的独立预测因素，但年轻患者则不然。术前患者自我报告的健康状况可能特别有助于细化风险分层并为老年患者心脏手术前后的决策提供信息。
The investigators assessed preoperative health-related quality of life as a predictor of 6-month mortality after cardiac surgery in older. (65 years of age and older) vs. younger patients. Multivariable regression, stratified by age groups, was used to compare the association between preoperative Physical Component Summary and Mental Component Summary scores from the Short Form-36 health status survey and mortality. In multivariable analyses of older patients, lower preoperative Physical Component Summary (odds ratio, 1.54; 95% confidence interval, 1.19-2.00; p=0.01) and Mental Component Summary (odds ratio, 1.26; 95% confidence interval, 1.06-1.49; p=0.03) scores were independently associated with mortality. In contrast, neither Physical Component Summary (p=0.82) nor Mental Component Summary (p=0.79) scores were associated with mortality in the younger subgroup. This study demonstrated that preoperative health status is an independent predictor of mortality following cardiac surgery in older but not younger patients. Preoperative patient self-report of health status may be particularly useful in refining risk stratification and informing decision-making before and following cardiac surgery in older patients.