[Research progress on sesquiterpenes and its pharmacological activities in genus Carpesium].
[Research progress on sesquiterpenes and its pharmacological activities in genus Carpesium].
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DOI：
10.19540/j.cnki.cjcmm.20190929.201
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发表时间：
2020-01-01
期刊：
影响因子：
--
通讯作者：
Zhou, Xiao-Jiang
中科院分区：
文献类型：
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作者：
Chen, Di-Lu;Li, Xuan;Zhou, Xiao-Jiang
摘要金雀花属植物含有多种倍半萜类化合物。迄今为止，已分离鉴定了201多个倍半萜类化合物，其中大根香叶内酯86个，桉烷内酯30个，愈创木内酯29个，倍半萜二聚体23个，假愈创木烷9个，卡拉烷内酯9个，黄原胶内酯7个，不含内酯的倍半萜6个，艾瑞莫芬烷1个，三环十二烷倍半萜1个。已报道的倍半萜类化合物具有抗肿瘤、抗炎、抗菌、抗寄生虫、杀虫、抗病毒等一系列药理活性。本文综述了201个金耳草属植物倍半萜类化合物的化学结构和生物活性，为进一步开发利用提供科学依据。
The genus Carpesium plants contain many kinds of sesquiterpenes. Up to now, more than 201 sesquiterpene compounds have been isolated and identified, including 86 germacranolides, 30 eudesmanolides, 29 guaianolides, 23 sesquiterpene dimers, 9 pseudoguaianes, 9 carabranolides, 7 xanthanolides, 6 sesquiterpenes without lactone, 1 eremophilane and 1 tricyclo dodecane sesquiterpene. The reported sesquiterpenes possess a series of pharmacological properties, such as anti-tumor, anti-inflammatory, antibacterial, antiparasitic, insecticidal, and antiviral activities. This paper summarizes the 201 chemical structures and biological activities of sesquiterpenes in genus Carpesium, and provides the scientific basis for the further development and utilization.