Timed Gait test: Normative data for the assessment of the AIDS dementia complex
Timed Gait test: Normative data for the assessment of the AIDS dementia complex
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DOI：
10.1080/13803390500205684
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发表时间：
2006-10-01
影响因子：
2.2
通讯作者：
Price, Richard W.
中科院分区：
文献类型：
--
作者：
Robertson, Kevin R.;Parsons, Thomas D.;Price, Richard W.
定时步态测试是一种评估与艾滋病痴呆相关的下肢运动功能障碍和步态异常的标准化程序。到目前为止，由于缺乏规范数据，对定时步态结果的解释受到阻碍。我们提供了来自1549名受试者（HIV血清阴性（HIV-）和血清阳性（HIV+）根据ADC分期分类）的该测试结果。定时步态被发现是评估ADC的有用筛选和评估工具，与临床ADC分期以及更广泛的结构化神经和神经心理学评估相关。协方差结果分析（以年龄和受教育程度为协变量）显示，有症状的HIV+(SX)和艾滋病组的计时步态评分明显低于HIV-和无症状的HIV+(ASX)组。SX组获得的计时步态评分明显低于艾滋病组。随着艾滋病毒痴呆分期的每一次增加，定时步态得分显著增加——受试者的平均定时步态得分最快，而艾滋病毒+痴呆2期+的得分最慢。这些标准数据应该证明对ADC的识别和治疗反应都是有用的。考虑到其最低的训练要求，定时步态将在资源有限的环境中发挥效用。
The Timed Gait test is a standardized procedure assessing motor dysfunction of lower extremities and gait abnormalities associated with AIDS dementia complex. Heretofore, interpretations of Timed Gait results have been hampered by the lack of normative data. We provide results on this test derived from 1,549 subjects (HIV-seronegatives (HIV-) and seropositives (HIV+) classified according to ADC stage). Timed Gait was found to be a useful screening and assessment tool for evaluating ADC and correlated with clinical ADC staging as well as more extensive structured neurological and neuropsychological evaluations. Analysis of covariance results (with age and education as covariates) revealed symptomatic HIV+(SX) and AIDS groups having significantly slower Timed Gait scores than those in the HIV- and asymptomatic HIV+(ASX) groups. The SX group obtained significantly slower timed gait scores than those in the AIDS group. There was a significant increase in Timed Gait scores with each increase in dementia staging with the HIV- subjects having the fastest mean Timed Gait scores and the HIV+ dementia stage 2+ having the slowest. These normative data should prove useful in both recognition of ADC and treatment response. Given its minimal training requirements, the Timed Gait would have utility in resource limited settings.