Risk factors for corneal abrasions in Nepal: a community-based study.
Risk factors for corneal abrasions in Nepal: a community-based study.
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尼泊尔角膜擦伤的危险因素：一项基于社区的研究。
DOI：
10.1038/s41433-023-02809-0
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发表时间：
2024
期刊：
影响因子：
--
通讯作者：
Ke
中科院分区：
文献类型：
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作者：
Brekke,SylviaR;Giri,Puspa;Byanju,Raghunandan;Pradhan,Sangita;Bhandari,Gopal;Bhandari,Sadhan;Kandel,RamPrasad;Poudyal,Bimal;Gonzales,JohnA;Srinivasan,Muthiah;Upadhyay,Madan;Whitcher,JohnP;O'Brien,KieranS;Lietman,ThomasM;Ke
背景南亚正经历着快速的城市化，这可能会改变眼外伤的危险因素。本研究的目的是比较在农村与城市尼泊尔的创伤性角膜擦伤的危险因素，并评估是否有任何危险因素与不良outcome.MethodsIn一个前瞻性的，横断面的，以社区为基础的研究进行了一个集群随机试验的一部分，来自尼泊尔的社区卫生工作者接受培训，以诊断和治疗创伤性角膜擦伤。有擦伤的参与者被邀请完成一项风险因素调查。主要暴露变量是眼损伤的对象，按农村-城市居住地分层。主要结果的措施是缺乏角膜愈合后，为期三天的课程的antimicrobials.ResultsOf 3657参与者诊断角膜擦伤，2265完成了调查。眼外伤最常发生在农业活动期间。最常见的伤害对象是植物性物质，约占农村、城郊和城市社区伤害的40%。木材伤害在农村社区（24%）比城市或城郊社区（13%）更常见。与其他类型的创伤（患病率2.59，95%CI 1.16-5.76）相比，动物的眼损伤在治疗3天后更可能导致不愈合的角膜擦伤（患病率2.59，95%CI 1.16-5.76）.ConclusionsHealth promotion activities for prevention of corneal ulcers in Nepal should focus on agricultural trauma in both rural and urban areas.遭受动物眼部创伤的社区成员可能会从早期转诊到眼科诊所中受益。
BackgroundSouth Asia is experiencing rapid urbanization, which may be changing the risk factor profile for ocular trauma. The objective of this study was to compare risk factors for traumatic corneal abrasions in rural versus urban Nepal, and to assess if any risk factors were associated with a poor outcome.MethodsIn a prospective, cross-sectional, community-based study performed as part of a cluster-randomized trial, community health workers from Nepal were trained to diagnose and treat traumatic corneal abrasions. Participants with an abrasion were invited to complete a risk factor survey. The main exposure variable was the object of eye injury, stratified by rural-urban residence. The main outcome measure was a lack of corneal healing after a three-day course of antimicrobials.ResultsOf 3657 participants diagnosed with a corneal abrasion, 2265 completed a survey. Eye trauma occurred most frequently during agricultural activities. The most common object of injury was vegetative matter, accounting for approximately 40% of injuries in rural, peri-urban, and urban communities. Wood injuries were more common in rural communities (24%) compared with urban or peri-urban communities (13%). Eye injury from an animal was more likely to result in a non-healing corneal abrasion after 3 days of treatment compared with other types of trauma (prevalence ratio 2.59, 95%CI 1.16–5.76).ConclusionsHealth promotion activities for prevention of corneal ulcers in Nepal should focus on agricultural trauma in both rural and urban areas. Community members experiencing eye trauma from an animal may benefit from early referral to an eye clinic.