The four epidemiological stages in the global evolution of inflammatory bowel disease.
The four epidemiological stages in the global evolution of inflammatory bowel disease.
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DOI：
10.1038/s41575-020-00360-x
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发表时间：
2021-01
期刊：
影响因子：
--
通讯作者：
Windsor JW
中科院分区：
文献类型：
--
作者：
Kaplan GG;Windsor JW
炎症性肠病（IBD）是一种全球性疾病，其演变可分为四个流行病学阶段：出现、发病加速、复合流行和流行平衡。2020年，发展中国家处于暴发阶段，新兴工业化国家处于发病加速阶段，西部地区处于复合流行阶段。西部地区最终将过渡到流行平衡阶段，在此阶段，随着IBD人群的老龄化，以及可能由于COVID-19大流行期间死亡率意外上升，加速的流行率将趋于平稳。减轻IBD的全球负担将需要在疾病预防和医疗保健提供创新方面做出共同努力，以应对全球IBD人口统计学的变化。在这个观点中，我们总结了IBD的全球流行病学，并利用这些数据将疾病演变分为四个流行病学阶段。炎症性肠道疾病（IBD）的全球负担正在不断变化。该观点总结了IBD的全球流行病学及其不断变化的疾病负担，假设疾病正在演变为四个流行病学阶段：出现，发病率加速，复合流行和流行平衡。
Inflammatory bowel disease (IBD) is a global disease; its evolution can be stratified into four epidemiological stages: Emergence, Acceleration in Incidence, Compounding Prevalence and Prevalence Equilibrium. In 2020, developing countries are in the Emergence stage, newly industrialized countries are in the Acceleration in Incidence stage, and Western regions are in the Compounding Prevalence stage. Western regions will eventually transition to the Prevalence Equilibrium stage, in which the accelerating prevalence levels off as the IBD population ages and possibly as a result of an unexpected rise in mortality during the COVID-19 pandemic. Mitigating the global burden of IBD will require concerted efforts in disease prevention and health-care delivery innovations that respond to changing demographics of the global IBD population. In this Perspective, we summarize the global epidemiology of IBD and use these data to stratify disease evolution into four epidemiological stages. The global burden of inflammatory bowel disease (IBD) is evolving. This Perspective summarizes the global epidemiology of IBD and its changing burden of disease, postulating that the disease is evolving into four epidemiological stages: Emergence, Acceleration in Incidence, Compounding Prevalence and Prevalence Equilibrium.
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影响因子：
9.8
作者：
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通讯作者：
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影响因子：
29.4
作者：
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通讯作者：
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影响因子：
24.5
作者：
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通讯作者：
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影响因子：
29.4
作者：
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通讯作者：
Kaplan, Gilaad G.
DOI：
10.1001/jama.1932.02740680019005
发表时间：
1932-07-01
影响因子：
--
作者：
Crohn, BB;Ginzburg, L;Oppenheimer, GD
通讯作者：
Oppenheimer, GD