Categorization is modulated by transcranial direct current stimulation over left prefrontal cortex.
Categorization is modulated by transcranial direct current stimulation over left prefrontal cortex.
复制标题
DOI：
10.1016/j.cognition.2012.04.002
复制
发表时间：
2012-07
期刊：
影响因子：
3.4
通讯作者：
Thompson-Schill SL
中科院分区：
文献类型：
--
作者：
Lupyan G;Mirman D;Hamilton R;Thompson-Schill SL
人类拥有无与伦比的能力，可以将对象表示为多个类别的成员。一个给定的对象，比如一个枕头，可以根据当前的任务需求，被表示为软的东西的实例，包含羽毛的东西，在卧室里找到的东西，或者比烤面包机大的东西。这种类型的处理要求个体动态地突出任务相关的属性，并抽象或抑制对象属性，虽然突出，但与手头的任务无关。神经影像学和神经心理学证据表明，这种能力可能取决于与左下前额叶回相关的认知控制过程。在这里，我们表明，刺激左下额叶皮层使用经颅直流电刺激改变一个简单的分类任务的健康受试者的性能。我们的任务要求受试者选择符合描述的图片，例如，"点击所有圆形的东西。“阴极刺激导致分类试验的表现较差，需要注意特定的尺寸，如颜色或形状，而不是需要选择属于更多主题类别的项目，如保持水的物体。极性反转（阳极刺激）降低了选择与目标类别关联更弱的项目的阈值。这些结果说明了前端介导的控制过程中的分类的作用，并建议分类，认知控制和语言之间的潜在的相互作用。
Humans have an unparalleled ability to represent objects as members of multiple categories. A given object, such as a pillow may be—depending on current task demands—represented as an instance of something that is soft, as something that contains feathers, as something that is found in bedrooms, or something that is larger than a toaster. This type of processing requires the individual to dynamically highlight task-relevant properties and abstract over or suppress object properties that, although salient, are not relevant to the task at hand. Neuroimaging and neuropsychological evidence suggests that this ability may depend on cognitive control processes associated with the left inferior prefrontal gyrus. Here, we show that stimulating the left inferior frontal cortex using transcranial direct current stimulation alters performance of healthy subjects on a simple categorization task. Our task required subjects to select pictures matching a description, e.g., “click on all the round things.“ Cathodal stimulation led to poorer performance on classification trials requiring attention to specific dimensions such as color or shape as opposed to trials that required selecting items belonging to a more thematic category such as objects that hold water. A polarity reversal (anodal stimulation) lowered the threshold for selecting items that were more weakly associated with the target category. These results illustrate the role of frontally-mediated control processes in categorization and suggest potential interactions between categorization, cognitive control, and language.
登录
查看更多内容
影响因子：
1.7
作者：
HINKE, RM;HU, XP;UGURBIL, K
通讯作者：
UGURBIL, K
影响因子：
2.3
作者：
COHEN, R;WOLL, G;EHRENSTEIN, WH
通讯作者：
EHRENSTEIN, WH
影响因子：
3.2
作者：
de Vries, Meinou H.;Barth, Andre C. R.;Floeel, Agnes
通讯作者：
Floeel, Agnes
影响因子：
4.1
作者：
Baddeley, A;Chincotta, D;Adlam, A
通讯作者：
Adlam, A
影响因子：
3.4
作者：
Goldstone, RL;Lippa, Y;Shiffrin, RM
通讯作者：
Shiffrin, RM