Elements concentrations in the scalp hair of methamphetamine abusers
Elements concentrations in the scalp hair of methamphetamine abusers
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甲基苯丙胺滥用者头皮中的元素浓度
DOI：
10.1016/j.forsciint.2015.01.016
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发表时间：
2015-04-01
影响因子：
2.2
通讯作者：
Ma, Dong
中科院分区：
文献类型：
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作者：
Luo, Ruxin;Zhang, Sujing;Ma, Dong
用电感耦合等离子体质谱法（ICP-MS）测定了40例甲基苯丙胺（METH）滥用者和对照者头发中As、Au、Ca、Cd、Co、Cr、Cu、Fe、Hg、Mg、Mn、Mo、Ni、Se、Sr和Zn等16种元素的含量。比较适当匹配的METH滥用者和对照组头发中的元素水平，发现滥用者和对照组之间的6种元素（As、Au、Ca、Cu、Mg和Sr）的浓度显著不平衡。与对照受试者相比，METH滥用者头发样本中的Ca（p <0.01）、Cu（p < 0.05）、Mg（p < 0.01）和Sr（p < 0.01）水平显著较低，而As（p < 0.01）和Au（p < 0.01）浓度较高。甲基苯丙胺滥用者头发中其余元素的浓度与对照组的浓度相似。呈现了METH滥用者和对照受试者头发中每种元素的几何平均值。本文还讨论了这些变化的原因。(C)2015爱思唯尔爱尔兰有限公司版权所有。
The concentrations of 16 elements (As, Au, Ca, Cd, Co, Cr, Cu, Fe, Hg, Mg, Mn, Mo, Ni, Se, Sr and Zn) in the hair of 40 methamphetamine (METH) abusers and control subjects were determined by inductively coupled plasma mass spectrometry (ICP-MS). Comparisons of the element levels in the hair of properly matched METH abuser and control groups revealed significant imbalances in the concentrations of 6 elements (As, Au, Ca, Cu, Mg and Sr) between the abuser and control groups. Ca (p < 0.01), Cu (p < 0.05), Mg (p < 0.01) and Sr (p < 0.01) levels are significantly lower in the hair samples of METH abusers compared to control subjects, whereas the As (p < 0.01) and Au (p < 0.01) concentrations are higher. The concentration of the remaining elements in the hair of METH abusers was similar to the concentration in the control subjects. The geometric means for each element in hair of METH abuser and control subjects are presented. The cause of these alterations is also discussed. (C) 2015 Elsevier Ireland Ltd. All rights reserved.