Predictive equations and the reliability of the impulse oscillatory system in Japanese adult subjects

Predictive equations and the reliability of the impulse oscillatory system in Japanese adult subjects
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DOI:
10.1111/j.1440-1843.2005.00703.x
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发表时间:
2005-06-01
期刊:
影响因子:
6.9
通讯作者:
Fukuchi, Y
Fukuchi, Y
中科院分区:
医学2区
文献类型:
--
作者:
Shiota, S;Katoh, M;Fukuchi, Y

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背景:脉冲振荡系统(IOS)以5赫兹的倍数的电阻(RRS)和电抗(XRS)测量呼吸阻抗(ZRS)。这些测量可用于临床诊断和监测呼吸疾病,而不需要付出任何努力。方法:首次确定了299名日本成人受试者在5和20赫兹的阻力和5赫兹的阻抗(R5,R20,X5)的预测方程。结果:R5、R20和X5的预测方程与受试者的吸烟史有明显差异(终生不吸烟者166人,调整后r分别为0.55、0.46和0.57;吸烟者133人,调整后r分别为0.47、0.42和0.47)。这种差异在性别上不那么明显(女性,n=120,调整后的r分别为0.42,0.20和0.47,与男性,n=179,调整后的r分别为0.46,0.37和0.47),预测方程依赖于R5和R20的身高对数(H),以及X5的年龄和身高对数。方程为:R5(kpa/L/S)=-3.841167 x Logh+8.671580;R20(kpa/L/S)=-2.546561 xlogH+5.841867;X5(kpa/L/S)=-0.000097 x年龄+1.018597 x Logh-2.343672。这些参数的日内重复性和日间差异均无统计学意义(P>0.05),提示IOS测量具有较高的重复性。结论:可以在日本成人受试者中确定IOS参数的预测方程并证实其高度可靠性。
Background: The impulse oscillation system (IOS) measures respiratory impedance (Zrs) in terms of resistance (Rrs) and reactance (Xrs) at multiples of 5 Hz. These Measurements can be used clinically to help diagnose and monitor respiratory disorders, independent of effort.Methodology: The predictive equation for resistance at 5 and 20 Hz and impedance at 5 Hz (R5, R20, X5), for the first time, in 299 Japanese adult subjects was determined. In addition, the within single day variation and between day variation were determined.Results: The predictive equation for R5, R20 and X5 revealed a clear difference with respect to the subject's smoking history (lifelong non-smoker, n = 166, adjusted r = 0.55, 0.46 and 0.57, respectively, vs. smoker, n = 133, adjusted r = 0.47, 0.42 and 0.47, respectively). This difference was less obvious with respect to gender (female, n = 120, adjusted r = 0.42, 0.20 and 0.47, respectively, vs. male, n = 179, adjusted r = 0.46, 0.37 and 0.47, respectively), The predictive equations were dependent on the log of height (H) for both R5 and R20, and on age and log of height for X5. The equations were: R5 (KPa/L/s) = -3.841167 x logH + 8.671580; R20 (KPa/L/s) = -2.546561 xlogH + 5.841867; and X5 (KPa/L/s) = -0.000097 x Age + 1.018597 x logH -2.343672. For these parameters there were no statistically significant differences for within day repeatability or between day variations (P > 0.05), suggesting a high degree of reproducibility for IOS measurements.Conclusion: It was possible to determine a predictive equation and confirm it high degree of reliability of IOS parameters in Japanese adult subjects.