Malononitrile as Acylanion Equivalent
Malononitrile as Acylanion Equivalent
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DOI：
10.1055/s-0028-1083540
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发表时间：
2008-11-14
期刊：
影响因子：
2
通讯作者：
Helmchen, Guenter
中科院分区：
文献类型：
--
作者：
Foerster, Sebastian;Tverskoy, Olena;Helmchen, Guenter
丙二腈的衍生物在甲醇中用过氧酸氧化，失去氰基，生成高产率的甲酯。该方法被应用于多种丙二腈衍生物，其中一些是通过Pd或Ir催化的不对称烯丙基取代反应制备的。
The oxidation of derivatives of malononitrile with peracid in methanol proceeds with loss of the cyano groups to yield methyl esters in high yield. The method was applied to a variety of malononitrile derivatives, some of which were prepared by Pd- or Ir-catalyzed asymmetric allylic substitution.