Study of Erythrocyte Aggregation by Blood Viscometry at Low Shear Rates Using a Balance Method
Study of Erythrocyte Aggregation by Blood Viscometry at Low Shear Rates Using a Balance Method
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使用平衡法在低剪切速率下通过血液粘度测定法研究红细胞聚集
作者：
A. M. Benis;J. Lacoste
用平衡法研究了血液在极低剪切速率下的粘度行为和聚集特性。该系统本质上是一个平行板粘度计，由一个薄薄的黄铜板由一根细线悬挂在分析梁天平的一端。通过记录应力松弛曲线，直接得到试样的屈服剪切应力。获得了均匀牛顿流体和非牛顿流体以及血液和各种红细胞悬浮液的结果。研究发现，人和狗的血液表现为表现屈服压力的液体。红细胞悬液在生理盐水中的屈服应力值要小得多，这与缺乏纤维蛋白原时红细胞聚集大大减少是一致的。屈服应力的测量值在0.001 ~ 0.1达因/cm2之间。
Abalance method was used to investigate the viscometric behavior and aggregation properties of blood at very low shear rates. The system was essentially a parallel-plate viscometer, consisting of a thin brass plate suspended by a fine wire from one end of an analytical beam balance. The yield shear stress of a sample was obtained directly by recording stress relaxation curves. Results were obtained for homogeneous Newtonian and non-Newtonian fluids and for blood and various red cell suspensions. It was found that human and canine blood behave as fluids exhibiting a yield stress. Suspensions of red cells in saline had much smaller values of yield stress, which is consistent with greatly diminished erythrocyte aggregation when fibrinogen is lacking. Measured values of the yield stress were in the range of 0.001 to 0.1 dynes/cm2.