Transcript design problem of oritatami systems
Transcript design problem of oritatami systems
复制标题
oritatami系统的抄本设计问题
DOI:
10.1007/s11047-019-09776-0
复制
发表时间:
2020
影响因子:
2.1
通讯作者:
Seki Shinnosuke
中科院分区:
文献类型:
--
作者:
Han Yo-Sub;Kim Hwee;Seki Shinnosuke
RNA cotranscriptional folding refers to the phenomenon in which an RNA transcript folds upon itself while being synthesized out of a gene. Oritatami model is a computation model of this phenomenon, which lets its sequence (transcript) of beads (abstract molecules) fold cotranscriptionally by the interactions between beads according to its ruleset. We study the problem of designing a transcript that folds into the given conformation using the given ruleset, which is called the transcript design problem. We prove that the problem is computationally difficult to solve (NP-hard). Then we design efficient poly-time algorithms with additional restrictions on the oritatami system.
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影响因子:
9.5
作者:
Churkin A;Retwitzer MD;Reinharz V;Ponty Y;Waldispühl J;Barash D
通讯作者:
Barash D
影响因子:
1.8
作者:
HOFACKER, IL;FONTANA, W;SCHUSTER, P
通讯作者:
SCHUSTER, P
DOI:
10.1007/978-3-030-00030-1_11
发表时间:
2018
期刊:
--
影响因子:
--
作者:
Yo;Hwee Kim
通讯作者:
Hwee Kim
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作者:
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通讯作者:
Stacho, Ladislav
DOI:
10.4230/lipics.isaac.2018.23
发表时间:
2018
期刊:
Proceedings of the 29th International Symposium on Algorithms and Computation (ISAAC 2018, Jiaoxi, Taiwan, Dec. 16-19, 2018)
影响因子:
--
作者:
Cody Geary;Pierre-Etienne Meunier;Nicolas Schabanel;Shinnosuke Seki
通讯作者:
Shinnosuke Seki