RADISH, A DROSOPHILA MUTANT DEFICIENT IN CONSOLIDATED MEMORY
RADISH, A DROSOPHILA MUTANT DEFICIENT IN CONSOLIDATED MEMORY
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DOI：
10.1073/pnas.90.17.8123
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发表时间：
1993-09-01
影响因子：
11.1
通讯作者：
QUINN, WG
中科院分区：
文献类型：
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作者：
FOLKERS, E;DRAIN, P;QUINN, WG
我们的特点是行为和遗传学的果蝇突变萝卜（rsh基因）。在两个嗅觉辨别测试中，萝卜蝇的初始学习是高的，但随后的记忆在训练后的早期和晚期都迅速衰减。训练后3小时，萝卜蝇的抗麻醉记忆（巩固记忆）不可检测。突变体显示出正常的运动活动和对气味线索和学习测试中使用的电击强化的正常敏感性。萝卜基因定位在X染色体11 D-E区域的180 kb间隔内。
We have characterized the behavior and genetics of the Drosophila mutant radish (rsh gene). Initial learning of radish flies in two olfactory discrimination tests is high, but subsequent memory decays rapidly at both early and late times after training. Anesthesia-resistant memory (consolidated memory) is undetectable in radish flies 3 hr after training. The mutant shows normal locomotor activity and normal sensitivity to the odor cues and electric-shock reinforcement used in the learning tests. The radish gene maps within a 180-kb interval in the 11D-E region of the X chromosome.