Cerenkov ultraviolet radiation (137Cs gamma-rays) and direct excitation (137Cs gamma-rays and 50 kVp X-rays) produce photoreactivable damage in Escherichia coli.
Cerenkov ultraviolet radiation (137Cs gamma-rays) and direct excitation (137Cs gamma-rays and 50 kVp X-rays) produce photoreactivable damage in Escherichia coli.
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切伦科夫紫外线辐射（137Cs 伽马射线）和直接激发（137Cs 伽马射线和 50 kVp X 射线）会对大肠杆菌产生光敏损伤。
DOI：
10.1080/09553008014551681
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
Smith,KC
中科院分区：
文献类型：
--
作者：
Moss,SH;Smith,KC
研究了一株暗修复缺陷的大肠杆菌(UVR A RecA)在电离辐射下对脱氧核糖核酸(DNA)光可再激活损伤的形成机制。通过改变直接(电离)造成的损害与间接(切伦科夫紫外线(UV)造成的损害)的比率。用~(137)Csγ射线研究表明，大部分的光可再激活损伤是由切伦科夫紫外光辐射产生的。不能产生切伦科夫辐射的50kVp X射线产生的光可再激活损伤的量类似于不能归因于切伦科夫辐射的137Csγ射线产生的可光再激活损伤的成分。结果表明，电离辐射对DNA的光可再激活损伤的第二种形成机制是DNA的直接激发。讨论了切伦科夫紫外线在电离辐射诱变中的可能作用。
The mechanism of formation of photoreactivable damage in deoxyribonucleic acid (DNA) by ionizing radiation in a dark repair deficient strain ofEscherichia coli(uvr A recA) has been investigated. By altering the ratio of damage produced directly (by ionization) to that formed indirectly (by Cerenkov ultraviolet (U.V.) radiation) by137Cs γ-rays, it has been demonstrated that the major portion of the photoreactivable damage is produced by Cerenkov U.V. radiation. The amount of photoreactivable damage produced by 50kVp X-rays, which cannot generate Cerenkov radiation, is similar to that component of photoreactivable damage produced by137Cs γ-rays that is not attributed to Cerenkov radiation. It is suggested that the second mechanism of formation of photoreactivable damage in DNA by ionizing radiation is the direct excitation of DNA. The possible role of Cerenkov U.V. radiation in ionizing radiation mutagenesis is discussed.