Integrated analytical sensors: the use of the TISPR-1 as a biosensor

Integrated analytical sensors: the use of the TISPR-1 as a biosensor
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DOI:
10.1016/s0925-4005(98)00336-0
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发表时间:
1999-01-25
影响因子:
8.4
通讯作者:
Melendez, JL
Melendez, JL
中科院分区:
化学1区
文献类型:
--
作者:
Elkind, JL;Stimpson, DI;Melendez, JL

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TISPR-1集成表面等离子体共振(SPR)传感器具有使其在分布式传感器环境中使用的理想功能。这种传感器,结合简单的生物薄膜,被证明能够进行各种各样的生物分析。本文介绍了肌酸激酶MB (CK-MB)的直接结合试验、二硝基苯酚-甘氨酸(DNP-GLY)的置换试验和三硝基甲苯(TNT)的竞争试验的数据。此外,还讨论了当前和预计的TISPR-1传感器系统的检测极限。(C) 1999 Elsevier Science S.A.版权所有
The TISPR-1 integrated surface plasmon resonance (SPR) sensor has features that make it ideal for use in a distributed sensor environment. This sensor, combined with simple bio-films, is shown to be capable of a wide variety of bio-assays. Data for a direct-binding assay for creatine kinase MB (CK-MB), for a displacement assay for dinitrophenol-glycine (DNP-GLY) and a competition assay for trinitrotoluene (TNT) are presented. Also, current and projected TISPR-1 sensor system limits of detection are discussed. (C) 1999 Elsevier Science S.A. All rights reserved.