THE INCIDENCE OF CANCER FOLLOWING TOTAL HIP-REPLACEMENT
THE INCIDENCE OF CANCER FOLLOWING TOTAL HIP-REPLACEMENT
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DOI：
10.1302/0301-620x.70b4.3403594
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发表时间：
1988-08-01
影响因子：
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通讯作者：
RYAN, PM
中科院分区：
文献类型：
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作者：
GILLESPIE, WJ;FRAMPTON, CMA;RYAN, PM
我们研究了全髋关节置换术后远端部位肿瘤的发生率：对1358例患者进行了14,286人-年的随访。在植入后的十年中，淋巴和造血系统肿瘤的发病率明显高于预期，而乳腺癌、结肠癌和直肠癌的发病率明显低于预期。虽然这种关联可能部分是由于假体植入物的影响，但其他机制，特别是药物治疗，需要考虑。
We have studied the incidence of tumours at remote sites following total hip replacement: 1 358 individuals have been followed up for 14,286 person-years after operation. In the decade following implantation the incidence of tumours of the lymphatic and haemopoietic systems significantly greater, and that of cancer of the breast, colon, and rectum, significantly less than expected. Whilst the association might be due in part to an effect of the prosthetic implants, other mechanisms, particularly drug therapy, require consideration.