Limitations in the assessment of DSM-IV cannabis tolerance as an indicator of dependence in adolescents
Limitations in the assessment of DSM-IV cannabis tolerance as an indicator of dependence in adolescents
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DOI：
10.1037/1064-1297.12.2.136
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发表时间：
2004-05-01
影响因子：
2.3
通讯作者：
Langenbucher, JW
中科院分区：
文献类型：
--
作者：
Chung, T;Martin, CS;Langenbucher, JW
《诊断和统计手册》（第4版）的实用性DSM-IV;美国精神病学协会，1994）作为依赖性指标的耐受性标准一直存在争议。这项研究的作者评估了DSM的大麻耐受性标准的性能，操作上定义为获得高水平所需数量的百分比增加，以区分有和没有大麻依赖的青少年。青少年大麻使用者（12-19岁）的两个样本提供了数据（ns = 417和380）。耐受性，定义为百分比增加（中位数增加= 300%和175%，分别在样品中），只有中等的整体灵敏度和特异性区分那些与大麻依赖和不依赖。结果表明，DSM-IV的变化为基础的操作定义的宽容在青少年的局限性。
The usefulness of the Diagnostic and Statistical Manual's (4th ed.; DSM-IV; American Psychiatric Association, 1994) tolerance criterion as an indicator of dependence has been debated. The authors of this study evaluated the performance of DSM's cannabis tolerance criterion, operationally defined as a percentage increase in quantity needed to get high, in distinguishing adolescents with and without cannabis dependence. Two samples of adolescent cannabis users (ages 12-19) provided data (ns = 417 and 380). Tolerance, defined as a percentage increase (median increase = 300% and 175%, respectively, in the samples), had only moderate overall sensitivity and specificity in distinguishing those with and without cannabis dependence. Results suggest limitations of the DSM-IV's change-based operational definition of tolerance in adolescents.