THE-PAQUID-EPIDEMIOLOGIC-PROGRAM-ON-BRAIN-AGING
THE-PAQUID-EPIDEMIOLOGIC-PROGRAM-ON-BRAIN-AGING
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DOI：
10.1159/000110955
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发表时间：
1992-01-01
影响因子：
5.7
通讯作者：
SALAMON, R
中科院分区：
文献类型：
--
作者：
DARTIGUES, JF;GAGNON, M;SALAMON, R
Paquid是一项流行病学研究，旨在收集和随访3，777名居住在家中的老年受试者（65岁及以上）。为了研究正常和病理性脑老化，这些受试者是在法国西南部两个行政区域吉伦特省和多尔多涅省的75个社区的普通人群中随机选择的。受试者在家中接受了训练有素的心理学家的采访，并在最初的数据收集后的1年，3年和5年进行了相同的程序。痴呆病例的识别采用两阶段设计：第一阶段是由心理学家应用DSM-IIIR标准进行系统筛查，第二阶段是由神经科医生根据NINCDS-ADRDA标准确认诊断。对生活在吉伦特省机构中的357名受试者进行随机抽样研究，补充了Paquid。
Paquid is an epidemiological study designed to gather and follow-up a cohort of 3,777 elderly subjects (65 years and older) living at home. In order to study normal and pathological brain ageing, these subjects were randomly chosen in the general population of 75 communities of Gironde and Dordogne, two administrative areas of South-Western France. The subjects were interviewed at home by trained psychologists and followed-up with the same procedure at 1, 3 and 5 years after the initial data collection. The identification of the demented cases is made with a two-stage design: the first stage is a systematic screening by the psychologists with application of the DSM-IIIR criteria and the second stage consists in a confirmation of the diagnosis by a neurologist according to the NINCDS-ADRDA criteria. Paquid is complemented by the study of a random sample of 357 subjects living in institutions in Gironde.