Quality of life and oral function in patients treated with radiation therapy for head and neck cancer
Quality of life and oral function in patients treated with radiation therapy for head and neck cancer
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DOI：
10.1002/hed.1049
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发表时间：
2001-05-01
影响因子：
2.9
通讯作者：
Stevenson-Moore, P
中科院分区：
文献类型：
--
作者：
Epstein, JB;Robertson, M;Stevenson-Moore, P
背景。头颈癌放射治疗期间出现多种口腔疾患，治疗后生活质量受到影响。本研究的目的是评估放疗期间和放疗后患者的生活质量、口腔功能和口腔症状。对连续接受头颈部恶性疾病放射治疗的患者进行一般生活质量调查(欧洲癌症研究和治疗组织（EORTC）生活质量问卷（QLQ-C30），并添加口腔症状和功能量表。患者在放射治疗开始时、治疗后立即和治疗后6个月完成调查。结果和讨论。本研究中使用的问卷提供了更多关于口腔和牙齿功能的信息，这些功能经常受到放射治疗的影响。本研究结果提示需要确定头颈癌治疗后的口腔功能障碍，以便选择对口腔功能和生活质量影响最小的恶性肿瘤最可预测的治疗或最佳姑息。头颈癌放射治疗期间和之后的口腔并发症是常见的，并影响生活质量。口服生活质量在放疗后6个月没有恢复到治疗前的水平。本研究支持使用通用功能量表，如EORTC问卷，并添加疾病/部位特异性量表，以提供治疗结果和治疗相关并发症的数据。EORTC qlq30问卷和口腔评估附录提供了头颈癌患者的生活质量和口腔功能的测量，并可能为评估这些患者群体的口腔护理预防和管理策略提供有用的结果测量。结果表明，调查问卷在头颈癌放射治疗的整个过程中对变化有反应。(C) 2001约翰威利父子公司
Background. Multiple oral complaints develop during radiation therapy for head and neck cancer, and quality of life is affected after treatment. The purpose of this investigation was to assess the quality of life, oral function, and oral symptoms in a cohort of patients during and after radiation therapy.Methods. A general quality of life survey (the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30), with an added oral symptom and function scale was administered to a consecutive series of patients who received radiation therapy for head and neck malignant disease. Patients completed surveys at the beginning of radiation therapy, immediately after, and 6 months after treatment.Results and Discussion. The questionnaire used in this study provides increased information regarding the oral and dental function that is frequently affected by radiation therapy. Results of this study indicate the need to determine oral dysfunction after head and neck cancer therapy, so that the most predictable cure or best palliation of the malignancy with the least impact on oral function and quality of life is chosen.Oral complications during and after radiation therapy for head and neck cancer are common and affect quality of life. Oral QOL does not return to pretreatment levels by 6 months after radiation therapy. This study supports the use of a general function scale such as the EORTC questionnaire with the addition of disease/ site-specific scales to provide data on outcomes of therapy and on the complications associated with therapy. The EORTC QLQ 30 questionnaire with the oral assessment addendum provides a measure of the quality of life and oral function in head and neck cancer patients and may provide useful outcome measures for assessment of oral care prevention and management strategies in these patient populations. The results show that the questionnaire is responsive to change throughout the course of radiation therapy for head and neck cancer. (C) 2001 John Wiley & Sons, Inc.