Human oesophageal adenocarcinoma cell lines JROECL 47 and JROECL 50 are admixtures of the human colon carcinoma cell line HCT 116.

Human oesophageal adenocarcinoma cell lines JROECL 47 and JROECL 50 are admixtures of the human colon carcinoma cell line HCT 116.
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DOI:
10.1054/bjoc.1999.1170
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发表时间:
2000-05
影响因子:
8.8
通讯作者:
Dinjens WN
Dinjens WN
中科院分区:
医学1区
文献类型:
--
作者:
Wijnhoven BP;Tilanus MG;Morris AG;Darnton SJ;Tilanus HW;Dinjens WN

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In two recently described human oesophageal adenocarcinoma cell lines JROECL 47 and JROECL 50, derived from one tumour, we detected identical E-cadherin and β-catenin gene mutations as in colon carcinoma cell line HCT 116. We demonstrate by HLA-typing, mutation analysis and microsatellite analysis that cell lines JROECL 47 and JROECL 50 are admixtures of the human colon adenocarcinoma cell line HCT 116. © 2000 Cancer Research Campaign