Single dose amoxicillin treatment of acute otitis media
Single dose amoxicillin treatment of acute otitis media
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单剂量阿莫西林治疗急性中耳炎
DOI：
10.1288/00005537-198701000-00006
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
J. aul O'Keefe
中科院分区：
文献类型：
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作者：
M. Puczynski;J. Stankiewicz;J. aul O'Keefe
进行了一项双盲研究，比较单剂量阿莫西林与阿莫西林 10 天疗程治疗急性中耳炎 (AOM) 的效果。所有在儿科诊所诊断为 AOM 的儿童都被要求参加。进行鼓室穿刺后，患者被随机分配接受阿莫西林（100 mg/kg）治疗，随后每 8 小时服用一次安慰剂，持续 10 天；或接受安慰剂，随后接受阿莫西林（40 mg/kg/D）治疗，持续 10 天。患者在治疗后第 3 天和第 10 天返回诊所。
A double blind study comparing a single dose of amoxicillin versus a 10‐day course of amoxicillin in the treatment of acute otitis media (AOM) was undertaken. All children diagnosed with AOM in a pediatric clinic were requested to participate. After tympanocentesis was performed, patients were randomly assigned to receive either amoxicillin (100 mg/kg) followed by placebo every 8 hours for 10 days or placebo followed by amoxicillin (40 mg/kg/D) for 10 days. Patients returned to clinic on days 3 and 10 post‐treatment.