Serum lipids in angiographically assessed coronary atherosclerosis.
Serum lipids in angiographically assessed coronary atherosclerosis.
复制标题
血管造影评估冠状动脉粥样硬化的血清脂质。
作者：
M. Frick;G. Dahlén;K. Berg;M. Valle;P. Hekali
对 153 名进行脂蛋白模式分型的患者的胆固醇、甘油三酯和 Lp(a)/前 β1 脂蛋白进行了分析。冠状动脉粥样硬化通过选择性冠状动脉造影确定，并通过考虑近端、中端和远端节段的系统进行分级。吸烟习惯、家族史和高血压也被记录。 45 名患者冠状动脉正常，50 名患者出现中度冠状动脉粥样硬化（评分低于中值），58 名患者出现严重变化（评分高于中值）。正常动脉组和整个管腔阻塞组之间的胆固醇（P小于0.05）、Lp（a）/前β1脂蛋白阳性（P小于0.01）、冠心病家族史（P小于0.05）和吸烟（P小于0.01）存在差异。血清甘油三酯与冠状动脉粥样硬化无关。胆固醇、Lp(a)/前β1脂蛋白阳性和冠心病家族史也与疾病的严重程度相关。在变化严重的组中，吸烟率较低。
Cholesterol, triglycerides, and Lp(a)/pre-beta1 lipoprotein were analyzed in 153 patients typed for liproprotien patterns. Coronary atherosclerosis was determined by selective coronary angiography and graded by a system taking into account proximal, middle and distal segments. Smoking habits, family history and hypertension were also recorded. Normal coronary arteries were encountered in 45, moderate coronary atherosclerosis (less than median score) in 50, and severe changes (greater than median score) in 58 patients. Cholesterol (P less than 0.05), positivity of Lp (a)/pre-beta1 lipoprotein (P less than 0.01), a family history of coronary heart disease (P less than 0.05), and smoking (P less than 0.01) differed between the group of normal arteries and the whole group of luminal obstructions. Serum triglycerides were not associated with coronary atherosclerosis. Cholesterol, positivity of the Lp(a)/pre-beta1 lipoprotein and a family history of coronary heart disease were also associated with the severity of the disease. Smoking was less prevalent in the group with severe changes.