Cytogenetic abnormalities in childhood acute lymphoblastic leukemia.
Cytogenetic abnormalities in childhood acute lymphoblastic leukemia.
复制标题
儿童急性淋巴细胞白血病的细胞遗传学异常。
DOI:
10.3109/08880019309016524
复制
发表时间:
1993
影响因子:
1.7
通讯作者:
P. M. Ellis
中科院分区:
文献类型:
--
作者:
P. Micallef;O. Eden;E. Grace;P. M. Ellis
A review of the cytogenetic analyses of a cohort of unselected patients with acute lymphoblastic leukemia from a single institution (1981-1989) confirmed hyperdiploidy > 50 as a favorable prognostic feature and pseudodiploidy, especially with chromosomal rearrangements, as an adverse one. In the early years of the study, a high incidence of diploid karyotype was identified, but with time (better banding and more intensive search) the incidence has fallen to 7.7%. Many such patients have been shown to be pseudodiploid. Molecular genetic techniques are increasingly identifying clonal abnormalities.
影响因子:
20.3
作者:
Pui,CH;Raimondi,SC;Dodge,RK;Rivera,GK;Fuchs,LA;Abromowitch,M;Look,AT;Furman,WL;Crist,WM;Williams,DL
通讯作者:
Williams,DL
影响因子:
20.3
作者:
D. Williams;J. Harber;S. Murphy;A. Look;D. Kalwinsky;G. Rivera;S. Melvin;S. Stass;G. Dahl
通讯作者:
D. Williams;J. Harber;S. Murphy;A. Look;D. Kalwinsky;G. Rivera;S. Melvin;S. Stass;G. Dahl
影响因子:
--
作者:
Williams,DL;Harris,A;Williams,KJ;Brosius,MJ;Lemonds,W
通讯作者:
Lemonds,W