Coronary calcium scoring: are the results comparable to computed tomography coronary angiography for screening coronary artery disease in a South Asian population?
Coronary calcium scoring: are the results comparable to computed tomography coronary angiography for screening coronary artery disease in a South Asian population?
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DOI：
10.1186/1756-0500-6-279
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发表时间：
2013-07-19
影响因子：
1.8
通讯作者：
Sajjad, Zafar
中科院分区：
文献类型：
--
作者：
Bhulani, Nizar;Khawaja, Ali;Sajjad, Zafar
背景：有可行的筛查工具，如冠状动脉钙化评分（CCS）和CT冠状动脉（CTCA）对冠状动脉疾病（CAD）的需求已经变得至关重要。我们的目的是在南亚人群中评估CCS与CTCA测定冠状动脉狭窄程度的准确性。方法：在阿迦汗大学医院进行回顾性研究。在2008年至2010年期间，共审查了539例接受CCS和CTCA的患者记录。通过比较他们的CCS和CTCA结果来审查患者记录。结果：301例CCS为0-9的患者中约有268例（89%）在CTCA上没有狭窄。在CCS为10-99的范围内，121例患者中有110例（91%）没有狭窄或有轻度狭窄。79例患者中约66例（84%）有中度或重度狭窄，钙评分为100-400，而没有一例患者没有狭窄。38例CCS超过400的患者中约有28例（74%）有严重狭窄。然而，只有04例患者（11%）被发现有轻度狭窄。Spearman的rho显示相关系数为0.791，p值为
BACKGROUND: The need of having feasible screening tools like Coronary Calcium Scoring (CCS) and CT Coronary Artery (CTCA) for Coronary Artery Disease (CAD) has become paramount. We aimed to evaluate the accuracy of CCS in determining the degree of stenosis of coronary vessels as compared to that determined by CTCA in a South Asian population.METHODS: A retrospective study was conducted at The Aga Khan University Hospital. A total of 539 patient records were reviewed who had undergone CCS and CTCA between 2008 and 2010. Patient records were reviewed by comparing their CCS and CTCA results.RESULTS: About 268 out of 301 (89%) patients with a CCS of 0-9 were found to be free of stenosis on CTCA. On a CCS of 10-99, 110 out of 121 (91%) patients were either free of stenosis or had mild stenosis. About 66 out of 79 (84%) patients had moderate or severe stenosis with a calcium score of 100-400 while none of the patients were free of stenosis. Around 28 out of 38 (74%) patients with a CCS of more than 400 had severe stenosis. However, only 04 patients (11%) were found to have mild stenosis. Spearman's rho revealed a correlation coefficient of 0.791 with a p-value of