Does processing of emotional stimuli predict symptomatic improvement and diagnostic recovery from major depression?
Does processing of emotional stimuli predict symptomatic improvement and diagnostic recovery from major depression?
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DOI：
10.1037/1528-3542.7.1.201
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发表时间：
2007-02-01
期刊：
影响因子：
4.2
通讯作者：
Gotlib, Ian H.
中科院分区：
文献类型：
--
作者：
Johnson, Sheri L.;Joormann, Jutta;Gotlib, Ian H.
本研究旨在探讨情绪刺激的处理是否可以预测抑郁症症状的改善和康复。被诊断为重度抑郁症（MDD）的参与者（N = 63）完成了信息处理任务，以评估对悲伤，身体威胁，社会威胁和快乐刺激的注意力和记忆。在平均9个月后的随访中，参与者被重新评估以确定诊断状态和抑郁严重程度。注意力或记忆力的测量都不能预测随访时的诊断状态。那些记住了更高比例的积极词汇的抑郁参与者，他们已经认可为自我描述，表现出更大的症状改善。在控制了积极的自我参照词的记忆后，注意力测量并不能预测症状的变化。这些结果与越来越多的文献一致，这些文献强调了情感相关记忆过程对理解重度抑郁症的重要性。
This study was designed to examine whether processing of emotional stimuli predicts both symptomatic improvement and recovery from depression. Participants diagnosed with Major Depressive Disorder (MDD) (N = 63) completed information-processing tasks to assess attention to and memory for sad, physically threatening, socially threatening, and happy stimuli. At a follow-up session an average of nine months later, participants were reassessed to determine diagnostic status and depression severity. None of the measure of attention or memory predicted diagnostic status at follow-up. Those depressed participants who remembered a higher proportion of positive words that they had endorsed as self-descriptive exhibited greater symptomatic improvement. After controlling for memory of positive self-referential words, attentional measures did not predict symptomatic change. These results are consistent with a growing literature highlighting the importance of emotionally relevant memory processes for understanding the course of major depression.