The cue-availability paradigm: The effects of cigarette availability on cue reactivity in smokers

The cue-availability paradigm: The effects of cigarette availability on cue reactivity in smokers
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DOI:
10.1037//1064-1297.9.2.183
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发表时间:
2001-05-01
影响因子:
2.3
通讯作者:
Tiffany, ST
Tiffany, ST
中科院分区:
医学3区
文献类型:
--
作者:
Carter, BL;Tiffany, ST

文献摘要

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研究人员假设,药物的可获得性应该影响成瘾者对药物相关刺激的反应,但对药物使用者在接触药物线索后获得药物的程度的操纵并没有产生强烈的可获得性效应。这项研究使用了会议内操纵的药物供应,以检查吸烟者的反应吸烟线索。吸烟者(N = 60)暴露于48次点燃的香烟或一杯水的试验,同时告知他们在每次试验中能够消耗提示的概率(0%,50%或100%)。结果从渴望,情绪,皮肤电导和潜伏期的措施,以访问的线索表明,一次又一次的试验操纵药物的可用性有显着的影响对香烟线索的反应。
Researchers have hypothesized that drug availability should influence addicts' reactions to drug-related stimuli, but manipulations of the extent to which drug users have access to their drugs following a session of exposure to drug cues have not produced strong availability effects. This study used within-session manipulations of drug availability to examine cigarette smokers' reactions to smoking cues. Smokers (N = 60) were exposed to 48 trials of either a lit cigarette or a glass of water while they were informed of the probability (0%, 50%, or 100%) that they would be able to consume the cue on each trial. Results from measures of craving, mood, skin conductance, and latency to access the cues indicated that the trial-by-trial manipulation of drug availability had a pronounced impact on reactivity to cigarette cues.