Infant feeding patterns in families with a diabetes history - observations from The Environmental Determinants of Diabetes in the Young (TEDDY) birth cohort study.
Infant feeding patterns in families with a diabetes history - observations from The Environmental Determinants of Diabetes in the Young (TEDDY) birth cohort study.
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DOI：
10.1017/s1368980013003054
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发表时间：
2014-12
影响因子：
3.2
通讯作者：
Virtanen, Suvi M.
中科院分区：
文献类型：
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作者：
Hummel, Sandra;Vehik, Kendra;Uusitalo, Ulla;McLeod, Wendy;Aronsson, Carin Andren;Frank, Nicole;Gesualdo, Patricia;Yang, Jimin;Norris, Jill M.;Virtanen, Suvi M.
评估糖尿病家族史与婴儿喂养方式之间的关系。在出生后的前24个月内，每隔3个月收集母乳喂养持续时间和首次引入牛奶和含谷蛋白谷物的年龄数据。数据来自多中心TEDDY（年轻人糖尿病的环境决定因素）研究，包括美国、瑞典、芬兰和德国的中心。共有7026名儿童，包括母亲患有1型糖尿病（T1 D; n 292）、妊娠期糖尿病（GDM; n 404）或无糖尿病但父亲和/或兄弟姐妹患有T1 D（n 464）的儿童和无糖尿病家族史的儿童（n 5866）。虽然纯母乳喂养结束较早，牛奶引入T1 D和GDM母亲的后代较早，但与无糖尿病家族史的婴儿相比，非糖尿病母亲但父亲和/或T1 D兄弟姐妹的后代纯母乳喂养时间更长，牛奶引入时间更晚。在调整临床变量（分娩方式、胎龄、Apgar评分和出生体重）后，母亲糖尿病和较短纯母乳喂养时间之间的关联减弱。针对具体国家的分析显示，这些关联存在差异，瑞典显示出最强的关联，芬兰显示母亲糖尿病与母乳喂养时间之间没有关联。糖尿病家族史与婴儿喂养模式有关;然而，各国之间的关联明显不同，表明文化差异是婴儿喂养行为的重要决定因素。在制定策略以改善有糖尿病家族史的婴儿的喂养模式时，需要考虑这些发现。
To assess the association between diabetes family history and infant feeding patterns. Data on breast-feeding duration and age at first introduction of cow’s milk and gluten-containing cereals were collected in 3-month intervals during the first 24 months of life. Data from the multicentre TEDDY (The Environmental Determinants of Diabetes in the Young) study, including centres in the USA, Sweden, Finland and Germany. A total of 7026 children, including children with a mother with type 1 diabetes (T1D; n 292), gestational diabetes mellitus (GDM; n 404) or without diabetes but with a father and/or sibling with T1D (n 464) and children without diabetes family history (n 5866). While exclusive breast-feeding ended earlier and cow’s milk was introduced earlier in offspring of mothers with T1D and GDM, offspring of non-diabetic mothers but a father and/or sibling with T1D were exclusively breast-fed longer and introduced to cow’s milk later compared with infants without diabetes family history. The association between maternal diabetes and shorter exclusive breast-feeding duration was attenuated after adjusting for clinical variables (delivery mode, gestational age, Apgar score and birth weight). Country-specific analyses revealed differences in these associations, with Sweden showing the strongest and Finland showing no association between maternal diabetes and breast-feeding duration. Family history of diabetes is associated with infant feeding patterns; however, the associations clearly differ by country, indicating that cultural differences are important determinants of infant feeding behaviour. These findings need to be considered when developing strategies to improve feeding patterns in infants with a diabetes family history.