Dyschromatosis symmetrica hereditaria (reticulate acropigmentation of Dohi): report of a Japanese family with the condition and a literature review of 185 cases
Dyschromatosis symmetrica hereditaria (reticulate acropigmentation of Dohi): report of a Japanese family with the condition and a literature review of 185 cases
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DOI：
10.1046/j.1365-2133.1999.02716.x
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发表时间：
1999-03
影响因子：
10.3
通讯作者：
M. Oyama;Hiroshi Shimizu;Yoshiyuki Ohata;Shingo Tajima;T. Nishikawa
中科院分区：
文献类型：
--
作者：
M. Oyama;Hiroshi Shimizu;Yoshiyuki Ohata;Shingo Tajima;T. Nishikawa
我们报告了一个日本家庭患有对称遗传性皮肤异常症（DSH） （MIM 127400在人类McKusick's孟德尔遗传），一种罕见的常染色体显性遗传性皮肤病，主要发生在日本和韩国个体。本家族患者表现出分布在面部和四肢背侧的色素沉着和色素沉着的混合斑，这是典型的DSH。由于大多数关于DSH的文献都是用日语写的，日本以外的皮肤科医生对这种疾病并不熟悉。本文回顾了185例DSH病例，其中大多数在日本报道，并描述了这种疾病独特的临床、组织学和遗传特征。
We report a Japanese family with dyschromatosis symmetrica hereditaria (DSH) (MIM 127400 in McKusick's Mendelian Inheritance in Man), a rare autosomal dominant genodermatosis, predominantly occurring among Japanese and Korean individuals. Members of the present family affected with the disease showed a mixture of hyperpigmented and hypopigmented macules distributed on the face and the dorsal aspects of the extremities, which are typical of DSH. As most of the literature on DSH has been written in Japanese, dermatologists outside Japan are not familiar with the condition. In this paper, 185 cases of DSH, most of them reported in Japanese, are reviewed and unique clinical, histological and genetic features of this condition are delineated.