Azide Conjugatable and pH Responsive Near-Infrared Fluorescent Imaging Probes
Azide Conjugatable and pH Responsive Near-Infrared Fluorescent Imaging Probes
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DOI：
10.1021/ol902140v
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发表时间：
2009-12-03
期刊：
影响因子：
5.2
通讯作者：
O'Shea, Donal F.
中科院分区：
文献类型：
--
作者：
Murtagh, Julie;Frimannsson, Daniel O.;O'Shea, Donal F.
描述了 pH 响应近红外荧光成像探针的合成和光物理特性。一个关键特征是能够通过炔-叠氮化物环加成反应结合探针，并且在生理 pH 范围内荧光强度可逆响应。
The synthesis and photophysical characteristics of a pH responsive near-infrared fluorescence imaging probe is described. A key feature is the ability to conjugate the probe by an alkyne-azide cycloaddition reaction and its reversible response of fluorescence intensity across the physiological pH range.