Predictors of battery life for the Activa® Soletra 7426 Neurostimulator
Predictors of battery life for the Activa® Soletra 7426 Neurostimulator
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DOI：
10.1016/j.parkreldis.2006.11.002
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发表时间：
2007-01-01
影响因子：
4.1
通讯作者：
Vuong, Kevin D.
中科院分区：
文献类型：
--
作者：
Ondo, William G.;Meilak, Catherine;Vuong, Kevin D.
DBS越来越多地用于帕金森氏症、特发性震颤和其他运动障碍。美敦力植入式脉冲发生器的宣传电池寿命为4.5年，但可能会有很大的差异。现有的理论公式可以预测电池寿命作为参数设置的函数，但几乎没有报道对这些预测进行经验验证。我们确定了实际失效电池和低压电池的所有电池更换。收集了人口统计数据，并纵向制定了该电池整个寿命的可调设置。通过基于Kaplan-Meier估计和对数等级检验的生存分析，评估了协变量对IPG装置寿命的个体贡献。我们在73名患者中更换了总共122个电池，其中男性50人(PD 42人，ET 29人，肌张力障碍2人，多发性硬化症1人)。这些更换的电池的中位寿命为37.4+/-17.3个月[范围：4-93个月]。完全用完的电池实际上在31.7+/-14.3个月[范围：4-74个月]内被更快地更换。在这组人中，电池寿命较短的主要预测因素是较大的幅度(p=0.002)、脉冲宽度(p=0.026)和不使用专用双极设置(p=0.029)。植入部位、潜在疾病和性别并不影响电池寿命。电池寿命有所不同，但总体上与已发表的预测结果一致。(C)2006爱思唯尔有限公司。保留所有权利。
DBS is increasingly used for Parkinson's disease, essential tremor and other movement disorders. The advertised battery life for Medtronic implantable pulse generators is 4 5 years, but can vary markedly. Theoretical formulas exist to predict battery life as a function of parameter setting, but almost no empiric confirmation of these predictions has been reported.We identified all battery replacements done for actual expired batteries and low voltage batteries. Demographic data were collected and the adjustable settings over the entire life of that battery were formulated longitudinally. The individual contributions of co-variables on the longevity of IPG devices were assessed by survival analysis based on the Kaplan-Meier estimator and log rank test.We have replaced a total of 122 batteries in 73 patients, 50 males (42 PD, 29 ET, two dystonias, one multiple sclerosis). The median life of these replaced batteries was 37.4 +/- 17.3 months [range: 4-93 months]. The batteries that completely expired were actually replaced sooner at 31.7 +/- 14.3 months [range: 4-74 months]. In this group, the main predictors of a shorter battery life were greater amplitude (p = 0.002), pulse width (p = 0.026), and not using exclusive bipolar settings (p = 0.029). The implant location, underlying disease, and sex did not affect battery life.Battery life varied but was generally consistent with published predictors. (C) 2006 Elsevier Ltd. All rights reserved.