Prophylactic ganciclovir treatment reduces fungal as well as cytomegalovirus infections after heart transplantation.
Prophylactic ganciclovir treatment reduces fungal as well as cytomegalovirus infections after heart transplantation.
复制标题
预防性更昔洛韦治疗可减少心脏移植后的真菌和巨细胞病毒感染。
DOI：
10.1097/00007890-199560120-00018
复制
发表时间：
1995
期刊：
影响因子：
6.2
通讯作者：
Stinson,EB
中科院分区：
文献类型：
--
作者：
Wagner,JA;Ross,H;Hunt,S;Gamberg,P;Valantine,H;Merigan,TC;Stinson,EB
巨细胞病毒（CMV）感染与器官移植受者其他机会性感染的发生率增加有关。这是否与CMV的免疫调节作用有关，或与CMV无关，但与两种感染共同的宿主危险因素有关，尚不清楚。本研究的目的是确定心脏移植术后预防性更昔洛韦治疗CMV感染的减少是否与其他机会性感染的发生率降低有关。
Cytomegalovirus (CMV) infection is associated with an increased incidence of other opportunistic infections in organ transplant recipients. Whether this is related to immunomodulating effects of CMV or independent of CMV but associated with a host risk factor common to both infections is unclear. The purpose of this study was to determine whether the reduction in CMV infections seen with prophylactic ganciclovir treatment after heart transplantation is associated with a reduced incidence of other opportunistic infections.