Zinc Supplementation in Treatment of Children With Urinary Tract Infection.
Zinc Supplementation in Treatment of Children With Urinary Tract Infection.
复制标题
补充锌治疗儿童尿路感染。
DOI：
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发表时间：
2016
影响因子：
1.3
通讯作者：
Aram Tabaei
中科院分区：
文献类型：
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作者：
P. Yousefichaijan;M. Naziri;Hassan Taherahmadi;M. Kahbazi;Aram Tabaei
介绍
泌尿道感染（UTI）在儿童中非常常见。早期诊断和适当的治疗是重要的，因为永久性疾病并发症。锌增加了许多感染的治疗反应。本研究旨在探讨锌在治疗UTI中的作用。
材料和方法
将200名UTI儿童分为2组，每组100名，他们在年龄、性别、尿液实验室特征、临床体征和症状方面具有可比性。对照组接受标准的UTI治疗方案，干预组接受口服硫酸锌糖浆加常规UTI治疗。
结果
接受锌治疗的患者恢复更快，但腹痛因锌而加剧，持续时间更长。治疗3个月后，两组患者退热时间、尿培养转阴时间比较差异无统计学意义。
结论
在患有UTI的儿童中，锌补充剂在改善严重排尿困难和尿频方面具有积极作用，而在存在腹痛的情况下不推荐使用这种药物。
INTRODUCTION
Urinary tract infection (UTI) is very common in children. Precocious diagnosis and appropriate treatment are important because of the permanent disease complications. Zinc increases the response to treatment in many infections. In this study, we explored the effect of zinc in treating UTI.
MATERIALS AND METHODS
Two hundred children with UTI were divided into 2 groups of 100 who were comparable in terms of age, sex, urine laboratory profiles, and clinical signs and symptoms. The control group received a standard treatment protocol for UTI and the intervention group received oral zinc sulfate syrup plus routine treatment of UTI.
RESULTS
A faster recovery was observed in the patients receiving zinc, but abdominal pain was exacerbated by zinc and lasted longer. Three months after the treatment, there was no significant difference between the two groups in the time of fever stop and negative urine culture.
CONCLUSIONS
In children with UTI, zinc supplementation has a positive effect in ameliorating severe dysuria and urinary frequency while the use of this medication is not recommended in the presence of abdominal pain.