Submacular perfluorocarbon liquid: long-term follow-up
Submacular perfluorocarbon liquid: long-term follow-up
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DOI：
10.1007/s10792-020-01287-7
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发表时间：
2020-01-24
影响因子：
1.6
通讯作者：
Zaky, Adel Galal
中科院分区：
文献类型：
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作者：
Ghoraba, Hamouda Hamdy;Ghoraba, Hashem Hamouda;Zaky, Adel Galal
目的报告玻璃体切除术后黄斑下氟碳液体（PFCL）气泡残留的长期随访结果。背景PFCL具有独特的化学和物理特征，可促进视网膜下液从中央向周边移位，从而允许术中重新附着移动的视网膜，并在不进行引流视网膜切开术的情况下操作脱离的视网膜的前部。尽管有这些优点，PFCL液滴可能会无意中保留在黄斑下空间。方法采用回顾性病例系列研究。我们回顾了1224例在一个玻璃体视网膜中心由单一外科医生（Hammouda Ghoraba）进行的原发性睫状体平坦部玻璃体切除术的连续患者。进行病历审查，以确定可能导致黄斑下PFCL残留的患者和手术因素，并随访至少18个月的解剖和功能结局。结果经1 ~ 2次玻璃体切除术后，PFCL组97%的眼视网膜完全复位。黄斑下PFCL 12只眼（0.98%）。全氟萘烷和全氟正辛烷之间的留存率没有统计学差异。与PFCL现象黄斑下滞留相关的可能危险因素是6例患者（50%）存在赤道后视网膜裂孔，3例患者（25%）存在大视网膜裂孔（2-3小时）。结论近1%的病例在使用人工晶状体时发生黄斑下PFC移位。它发生在赤道后或大断裂的RRD病例中。使用全氟正辛烷或全氟萘烷没有统计学差异。黄斑下PFC液滴的行为不同。部分黄斑下PFC液滴较小的病例可长期保持较好的视力。
Purpose To report the long-term follow-up of patients with inadvertent retained submacular perfluorocarbon liquid (PFCL) bubbles after vitrectomy surgery. Background PFCL has unique chemical and physical features which facilitate displacement of subretinal fluid from central toward periphery allowing intraoperative reattachment of the mobile retina and manipulation of the anterior part of the detached retina without performing drainage retinotomy. Despite these advantages, PFCL droplets may be inadvertently retained in the submacular space. Methods A retrospective case series study was conducted. We reviewed 1224 consecutive patients who had undergone primary pars plana vitrectomy at one vitreoretinal center operated by single surgeon (Hammouda Ghoraba). Chart review was performed to identify patients and procedural factors that could predispose to retained submacular PFCL with anatomical and functional outcomes with follow-up at least 18 months. Results The retina was completely attached in 97% of eyes where PFCL was used after one or two vitrectomy surgeries. Submacular PFCL was found in 12 (0.98%) eyes. There was no statistical difference between perfluorodecalin and perfluoro-n-octane as regards retention rate. The possible risk factors associated with submacular retention of PFCL phenomenon are the presence of post-equatorial retinal breaks in six patients (50%) and large retinal break (2-3 clock hours) in three patients (25%). Conclusions Submacular PFC migration occurs in nearly 1% of cases when it is used. It occurred in cases of RRD with post-equatorial or large breaks. Using perfluoro-n-octane or perfluorodecalin had no statistical difference. Different behaviors of submacular PFC droplets occurred. Some cases of small submacular PFC droplets maintained fair VA for a long period.