Performance measurements of a depth-encoding PET detector module based on position-sensitive avalanche photodiode read-out
Performance measurements of a depth-encoding PET detector module based on position-sensitive avalanche photodiode read-out
复制标题
DOI：
10.1088/0031-9155/49/18/007
复制
发表时间：
2004-09-21
影响因子：
3.5
通讯作者：
Cherry, SR
中科院分区：
文献类型：
--
作者：
Dokhale, PA;Silverman, RW;Cherry, SR
我们正在开发一种高分辨率，高效率的正电子发射断层扫描（PET）探测器模块的相互作用深度（DOI）的能力的基础上的氧硅酸镥（LSO）闪烁体阵列耦合在两端的位置敏感的雪崩光电二极管（PSAPDs）。在本文中，我们提出了完整的探测器模块的DOI分辨率，能量分辨率和时间分辨率的结果。探测器模块由一个7 x 7矩阵的LSO闪烁体晶体（尺寸为1 x 1 x 20 mm（3））组成，两端耦合到8 X 8 mm（2）PSAPD。获得洪水直方图并用于生成晶体查找表。通过使用来自两个PSAPD的信号幅度的比率，在逐个事件的基础上，测量阵列内单个晶体的DOI分辨率。通过对来自两个PSAPD的信号幅度求和来获得产生的总闪烁光的测量。该求和信号用于测量能量分辨率。DOI分辨率被测量为3-4 mm FWHM，而与晶体在阵列内的位置或沿着晶体长度的相互作用位置无关。总的光信号和能量分辨率几乎与相互作用的深度无关。测量的能量分辨率平均为14%FWHM。使用一对相同的探测器模块测量的符合定时分辨率为4.5 ns FWHM。这些结果与小型动物和乳腺成像应用的紧凑型、高分辨率和高效率PET探测器模块的设计目标和所需性能一致。
We are developing a high-resolution, high-efficiency positron emission tomography (PET) detector module with depth of interaction (DOI) capability based on a lutetium oxyorthosilicate (LSO) scintillator array coupled at both ends to position-sensitive avalanche photodiodes (PSAPDs). In this paper we present the DOI resolution, energy resolution and timing resolution results for complete detector modules. The detector module consists of a 7 x 7 matrix of LSO scintillator crystals (1 x 1 x 20 mm(3) in dimension) coupled to 8 X 8 mm(2) PSAPDs at both ends. Flood histograms were acquired and used to generate crystal look-up tables. The DOI resolution was measured for individual crystals within the array by using the ratio of the signal amplitudes from the two PSAPDs on an event-by-event basis. A measure of the total scintillation light produced was obtained by summing the signal amplitudes from the two PSAPDs. This summed signal was used to measure the energy resolution. The DOI resolution was measured to be 3-4 mm FWHM irrespective of the position of the crystal within the array, or the interaction location along the length of the crystal. The total light signal and energy resolution was almost independent of the depth of interaction. The measured energy resolution averaged 14% FWHM. The coincidence timing resolution measured using a pair of identical detector modules was 4.5 ns FWHM. These results are consistent with the design goals and the performance required of a compact, high-resolution and high-efficiency PET detector module for small animal and breast imaging applications.