The DC-SQUID-based Magnetocardiographic Systems for Clinical Use
The DC-SQUID-based Magnetocardiographic Systems for Clinical Use
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基于 DC-SQUID 的临床心磁图系统
DOI：
10.1016/j.phpro.2012.06.218
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
A. Gapelyuk
中科院分区：
文献类型：
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作者：
Y. Maslennikov;M. Primin;V. Slobodchikov;V. Khanin;I. Nedayvoda;V. Krymov;A. V. Okunev;É. A. Moiseenko;A. V. Beljaev;V. S. Rybkin;A. V. Tolcheev;A. Gapelyuk
基于dc- squid的新型心脏磁图（MCG）系统（命名为“MAG-SCAN”系列）经过设计、制造和测试。这些系统的目的是常规的MCG调查的病人在实际的临床电生理实验室条件。“MAG-SCAN”系列包括硬件和软件兼容的MCG设备系列，测量通道数量从1到36。7通道和9通道mcg系统的实验原型（由CRYOTON有限公司制造的模型“MAG-SCAN-07”和“MAG-SCAN-09”）安装在莫斯科市的几家医院中，并在常规临床实验室的无屏蔽环境中运行。平衡良好的二阶梯度仪已被用于MCG数据记录。他们证明了固有噪声水平优于5 fT/√Hz。在莫斯科城市条件下测量了约20-40 fT/√Hz的总噪声级。特殊软件包（命名为“SOFTMAG”）被开发为两个自主子系统，允许对心磁信号进行预处理，并对场特征和场源进行时空分析。该软件采用该算法对心脏磁场的时空特征和相应的电流分布进行分析和估计。研究人员对包括健康人、高血压、缺血性疾病（IHD）、慢性阻塞性肺疾病（COPD）和支气管哮喘（BA）患者在内的2000多名不同的志愿者进行了调查，并为每组患者找到了一组特定的mcg参数。
The new line of dc-SQUID-based magnetocardiographic (MCG) systems (named as the “MAG-SCAN”-family) is designed, fabricated and tested. These systems are intended for routine MCG investigations of patients at conditions of real clinical electrophysiological labs. The “MAG-SCAN”-family includes the line of MCG devices compatible in terms of hardware and software with number of measuring channels from 1 to 36. Experimental prototypes of 7- and 9-channel MCG-systems (the models “MAG-SCAN-07” and “MAG-SCAN-09” fabricated at CRYOTON Co. Ltd.) were installed in a few hospitals of Moscow city and operated in an unshielded environment of usual clinical labs. Well balanced second-order gradiometers have been used for MCG data recording. They demonstrated an intrinsic noise level better than 5 fT/√Hz. The total noise level of about 20-40 fT/√Hz was measured at urban conditions of Moscow city. The package of special software (named as the “SOFTMAG”) was developed as two autonomous subsystems that allow the preprocessing of the heart magnetic signals and the spatio-temporal analysis of the field characteristics and the field sources. The software employs the algorithms for the analysis and estimation of the spatio-temporal characteristics of the heart magnetic field and the correspondent electrical currents distributions. More than 2000 investigations of different volunteers including healthy persons, patients with high blood-pressure, ischemic disease (IHD), chronic obstructive pulmonary disease (COPD) and bronchial asthma (BA) were carried out and sets of MCG-parameters specific for each group were found.