T cell suppression of contact sensitivity in the mouse. III. The role of macrophages and the specific triggering of nonspecific suppression
T cell suppression of contact sensitivity in the mouse. III. The role of macrophages and the specific triggering of nonspecific suppression
复制标题
T 细胞抑制小鼠的接触敏感性。
DOI：
10.1002/eji.1830041207
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发表时间：
1974
影响因子：
5.4
通讯作者：
M. Zembala
中科院分区：
文献类型：
--
作者：
G. Asherson;M. Zembala
淋巴结细胞对接触敏感性的被动转移和对接触敏感性的抑制可通过抗-Θ血清和补体治疗消除。相反，腹膜渗出细胞的这两种形式的被动转移抵抗抗-Θ血清的处理，但被胰蛋白酶消除。这表明腹膜渗出液中的负责细胞是巨噬细胞或其他Θ阴性细胞。
Passive transfer of contact sensitivity and suppression of contact sensitivity by lymph node cells is abolished by treatment with anti‐Θ serum and complement. In contrast, both these forms of passive transfer by peritoneal exudate cells resist treatment with anti‐Θ serum but are abolished by trypsin. This suggests that the cell responsible in the peritoneal exudate is a macrophage or other Θ‐negative cell.