Estimation of the prevalence, incidence, comorbidities and direct costs associated to stroke patients requiring care in an area of the Spanish population
Estimation of the prevalence, incidence, comorbidities and direct costs associated to stroke patients requiring care in an area of the Spanish population
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DOI：
10.33588/rn.4607.2008052
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发表时间：
2008-04-01
影响因子：
1.2
通讯作者：
Ezpeleta-Echevarri, D.
中科院分区：
文献类型：
--
作者：
de Bobadilla, J. Fernandez;Sicras-Mainar, A.;Ezpeleta-Echevarri, D.
瞄准。确定西班牙人群中中风的患病率、发病率、并存情况、治疗目标和费用。病人和方法。一项基于2006年西班牙五个初级保健中心和两家医院的30岁中风患者的数据进行了回溯性研究。对照组：无卒中患者。主要分析变量有：年龄、性别、合并症(心血管疾病/其他)、临床参数和直接成本(药房、衍生产品、就诊、紧急情况、采购和住院)。采用方差分析和Logistic回归分析对模型进行拟合。结果。57.026例患者中有4.5%发生中风(n=2.585；CI 95%=4.3-4.7%)。卒中发病率为2 2 0例/100.000人。中风患者和对照组之间的主要差异是：年龄(72.5比53.5)，男性(58.2%比44.6%)，发作/年(7，9比4，8)，就诊/年(15，8比8，1)，P<；0,001。年龄(OR=1，4)、男性(OR=2，3)、糖尿病(OR=1，6)、高血压(OR=1，5)、吸烟(OR=1，5)、饮酒(OR=1，4)、抑郁(OR=1，4)、血脂异常(OR=1，3)和痴呆(OR=1，2)与卒中有独立关系。其中一些结果是：收缩压(134.1比127.6毫米汞柱)和低密度脂蛋白-胆固醇(116.4比126.2毫克/分升)，在有或没有中风的情况下，p<；0，00/。中风的年平均成本为2590.36欧元，P<；为985.26欧元，P<；为0.001欧元。修正后的Logistic模型结果没有变化：1,774.33欧元(CI 95%=1,720.10-1.828.55)与1,021.98欧元(CI 95%=1,010.92-1,033.03)，p<；0,001。中风组的所有费用组成部分都较高。结论。需要帮助治疗中风的患者有更多的共病数量和更高的总成本/患者/年治疗目标可以改善，主要是在心血管危险因素的一级预防方面。
Aim. To determinate the prevalence, incidence, co-morbidities and therapeutic objectives and costs of stroke among Spanish population. Patients and methods. A retrospective study was performed based on data from patients attended for stroke, aged > 30 years, from five Spanish primary care centres and two hospitals in 2006. Comparative group: patients without stroke. Main analysed variables were: age, sex, co-morbidity (cardiovascular/others), clinical parameters and direct costs (pharmacy, derivations, visits, emergencies, procurement, and hospitalisation). An ANCOVA analysis and logistic regression were used to fit the model. Results. A 4.5% of 57.026 patients (n = 2.585; CI 95% = 4.3-4.7%) suffered stroke. The incidence of stroke was 220 new-case/100.000 populations. Main differences between patients suffering stroke/control group were: age (72.5 vs. 53.5), men (58.2% vs. 44.6%), episodes/year (7,9 vs. 4,8), visits/year (15,8 vs. 8, 1), p < 0,001. Stroke had an independent relation with age (OR = 1,4), male (OR = 2,3), diabetes (OR = 1,6), hypertension (OR = 1,5), smoking (OR = 1,5), alcohol (OR = 1,4), depression (OR = 1,4), dyslipidemia (OR = 1,3) and dementia (OR = 1,2). Some of the results were: systolic pressure (134.1 vs. 127.6 mmHg) and LDL-cholesterol (116.4 vs. 126.2 mg/dL), in presence/absence of stroke, p < 0,00/. The average of annual costs of stroke was 2,590.36 vs. 985.26 euros, p < 0.001. After the correction of the logistic model results did not change: 1, 774.33 (CI 95% = 1, 720.10-1.828.55) vs. 1,021.98 euros (CI 95% = 1,010.92-1,033.03), p < 0,001. All components of costs were higher in the stroke group. Conclusions. patients that demanded assistance for stroke had a higher number of co-morbidities and a higher total cost/patient/year Therapeutic objectives could be improved, mainly in primary prevention of cardiovascular risk factors.