Epidemiology of penicillinase-producing Neisseria gonorrhoeae infections: analysis by auxotyping and serogrouping.
Epidemiology of penicillinase-producing Neisseria gonorrhoeae infections: analysis by auxotyping and serogrouping.
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产生青霉素酶的淋病奈瑟菌感染的流行病学:通过基因型和血清分型进行分析。
DOI:
10.1056/nejm198204223061602
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发表时间:
1982
期刊:
影响因子:
--
通讯作者:
Holmes,KK
中科院分区:
文献类型:
--
作者:
Handsfield,HH;Sandstrom,EG;Knapp,JS;Perine,PL;Whittington,WL;Sayers,DE;Holmes,KK
Auxotyping and serogrouping by coagglutination were used to characterize penicillinase-producingNeisseria gonorrhoeaeand penicillinase-negative isolates from the state of Washington, Shreveport (Louisiana), and the Far East. Fifty-four of 75 penicillinase-producing isolates (72 per cent) from Washington required proline for growth and were serogroup W-I (Pro-I), the predominant type of penicillinase-producing strains in the Philippines; none of 86 penicillinase-negative isolates from Washington was Pro-I (P<0.0001). All 38 penicillinase-producing isolates from Shreveport required proline and were serogroup W-II (Pro-II); five of 26 penicillinase-negative isolates (19 per cent) from Shreveport were also Pro-II (P<0.0001) but had antigenic specificities within serogroup W-II that distinguished them from the penicillinase-producing isolates. We conclude that the Washington and Shreveport outbreaks resulted from the spread of imported strains rather than transmission of penicillinase-encoding plasmids to indigenous gonococci. The Shreveport outbreak involved a single strain of penicillinase-producingN. gonorrhoeaeand probably originated from a common source, whereas several types were involved in the multiple-source Washington outbreak, indicating repeated introduction of new strains. (N Engl J Med. 1982; 306:950–4.)
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DOI:
10.1121/1.385953
发表时间:
1981
期刊:
The Journal of the Acoustical Society of America
影响因子:
--
作者:
Javel,E
通讯作者:
Javel,E
影响因子:
2.4
作者:
M. Sachs;E. Young
通讯作者:
E. Young
影响因子:
2.4
作者:
YOUNG, ED;SACHS, MB
通讯作者:
SACHS, MB
DOI:
10.1121/1.386208
发表时间:
1981-05
期刊:
The Journal of the Acoustical Society of America
影响因子:
--
作者:
D. Sinex;C. Geisler
通讯作者:
D. Sinex;C. Geisler
影响因子:
2.4
作者:
Paul J. Abbas;M. Sachs
通讯作者:
M. Sachs