MHC superfamily structure and the immune system

MHC superfamily structure and the immune system
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DOI:
10.1016/s0959-440x(99)00039-1
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发表时间:
1999-12-01
影响因子:
6.8
通讯作者:
Jones, EY
Jones, EY
中科院分区:
生物学2区
文献类型:
--
作者:
Maenaka, K;Jones, EY

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在过去的一年中,大量的结构信息提供了详细的见解经典的MHC I类分子和T细胞上的同源受体之间的相互作用。同样,我们对五种非经典MHC样分子的结构和功能的认识也取得了重大进展:HLA-DM(鼠H2-M)、HLA-E、HFE、ZAG和MIC-A。
During the past year, a plethora of structural information has provided detailed insights into the interactions between classical MHC class I molecules and their cognate receptors on T cells. Likewise, there have been major advances in our knowledge of the structures and functions of five nonclassical MHC-like molecules: HLA-DM (murine H2-M), HLA-E, HFE, ZAG and MIC-A.