Renal tubule ion transport and collecting duct function in the elasmobranch little skate, Raja erinacea.
Renal tubule ion transport and collecting duct function in the elasmobranch little skate, Raja erinacea.
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软骨鱼小鳐（Raja erinacea）的肾小管离子运输和集合管功能。
DOI：
10.1002/jez.1401990314
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发表时间：
1977
期刊：
影响因子：
--
通讯作者：
U. Niermann
中科院分区：
文献类型：
--
作者：
H. Stolte;R. Galaske;G. Eisenbach;C. Lechene;B. Schmidt;J. Boylan;D. Antkowiak;Y. Patel;U. Niermann
应用肾微穿刺和显微切割技术结合超微流体分析，对棘鳐单个肾单位的功能进行了研究。我们将旱冰鱼肾单位分为三个近端小管段（PTS Ⅰ-Ⅲ）、三个远端管段（DC Ⅰ-Ⅲ）和一个位于近端小管段和远端管段之间的逆流环路系统。集合管是尿液稀释的主要部位。在将鱼暴露于75%海水约24小时后，末端收集管腔和血浆之间的钠浓度差降低到足以解释尿稀释。镁、磷酸盐和硫酸盐分泌的主要部位似乎是PTS II。该节段位于肾脏的腹侧表面上。PTS II也是重吸收过量水的钠和氯化物的主要肾单位。
Renal micropuncture and microdissection techniques with ultramicro fluid analysis have been applied to evaluate single nephron function in the skate, Raja erinacea. We have divided the skate nephron into three proximal tubular segments (PTS I-III), three distal coilings (DC I-III), and a countercurrent loop system located between the proximal segments and the distal coilings. The collecting duct is the principal site of urinary dilution. Following exposure of the fish to 75% seawater for about 24 hours, the sodium concentration difference between the end collecting duct lumen and plasma is decreased sufficiently to account for the urinary dilution. The principal site for magnesium, phosphate and sulphate secretion appears to be PTS II. This segment is located on the ventral surface of the kidney. PTS II is also the main nephron site for reabsorption of sodium and chloride in excess of water.