Influence of a fluoride mouthrinse on mutans streptococci in schoolchildren
Influence of a fluoride mouthrinse on mutans streptococci in schoolchildren
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DOI：
10.1159/000095649
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发表时间：
2006-01-01
期刊：
影响因子：
4.2
通讯作者：
Miyazaki, Hideo
中科院分区：
文献类型：
--
作者：
Kaneko, Noboru;Yoshihara, Akihiro;Miyazaki, Hideo
本研究旨在确定长期使用含氟漱口水是否会影响唾液中变形链球菌的水平。215名学童（9-10岁）参加了培训。其中149名儿童从5岁起在幼儿园使用含氟漱口水，其余66名儿童没有使用过。DFT（龋齿和填充牙）记录，并使用缓和唾液杆菌肽琼脂测量唾液中变形链球菌和远缘链球菌的水平。使用含氟漱口水的一组人的两种S。变异株和S. sobrinus组（p = 0.038）和DFT评分显著低于其他组（p = 0.001）。以基线患龋经历为因变量进行Logistic回归分析，结果显示，患龋的优势比为0.001，患龋的优势比为0.001。单携带变形链球菌的阳性率为8.0（p = 0.066），同时携带变形链球菌和变形链球菌的阳性率为8.0（p = 0.066）。mutans和S.在未使用含氟漱口水的组中，sobrinus为16.5（p = 0.022）。携带两种S的儿童。mutans和S. sobrinus在1年内患龋率高于其他两组，优势比为5.73（p = 0.067）在含氟漱口水组和3.47（p = 0.035）。这些结果表明，长-长期使用含氟漱口水与唾液中变异链球菌水平的降低有关，这种细菌减少可能部分有助于长期使用含氟漱口水抑制儿童龋齿。版权所有（c）2006 S. Karger AG，巴塞尔
This study aimed to determine whether the long-term use of a fluoride mouthrinse affects the salivary levels of mutans streptococci. Two hundred and fifteen schoolchildren (aged 9-10 years) participated. One hundred and forty-nine of these children had used a fluoride mouthrinse since 5 years of age at nursery school, and the remaining 66 children had not. DFT (decayed and filled teeth) was recorded, and the salivary levels of Streptococcus mutans and Streptococcus sobrinus were measured using mitis salivarius bacitracin agar. The group that had used a fluoride mouthrinse had a significantly lower prevalence of both S. mutans and S. sobrinus (p = 0.038) and a significantly lower DFT score (p = 0.001) than the other group. Using logistic regression analysis including caries experience at baseline as a dependent variable, the odds ratio of carrying S. mutans alone was 8.0 (p = 0.066) and that of carrying both S. mutans and S. sobrinus was 16.5 (p = 0.022) in the group that had not used the fluoride mouthrinse. Children carrying both S. mutans and S. sobrinus had a higher caries incidence in 1 year than the others, with odds ratios of 5.73 ( p = 0.067) in the group with a fluoride mouthrinse and 3.47 (p = 0.035) in the group without it. These results show that the long-term use of a fluoride mouthrinse is associated with reduced salivary levels of mutans streptococci and this bacterial reduction may partly contribute to the suppression of dental caries in children using a long-term fluoride mouthrinse. Copyright (c) 2006 S. Karger AG, Basel